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11?5?,??,?????????????????????????????????????????,?“????”????????????????????????????????????????????????????“???????????????????????????”????????,?????????????????,??????????????????,???????????????????????????

???????????????????:????113???

11?7?????????,????,????????????40??????????????????????????????????????????,??????????????????????????“??????”????????????????30??,????????,113???????«????????????????????????(ICD-11)»?????,???????????????????,????????????????????????,???????????????ISO/TC249,??????????113??????????????????

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?14.1?????????????????

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11?????????????8????,??????,???????????HRS-2189?????????HRS-5041 ??HRS-1358??HRS-8080????SHR-8068???????????????????????????????????????????????HRS-620 ????«?»,???????????????????

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11??????????????8?????????,??????,?(FDA)???????????????(New Drug Application,NDA),?,???? FDA ????????,????????(EGFR)20 ???????(Exon20ins)?(NSCLC)????????????????????????????????????????? FDA ???????

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11??????????9????????????,????????,???????????????KRAS G12C?(??“????”)??????,??????????????????KRAS G12C?(NSCLC)??????????,???????????,?????????????????1????????????????????????????????????,??5????,???6????????????KRAS G12C?,????????????KRAS G12C???????

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11??????????????????7?????????,?«?????»?«????????»????????????????????????,????????,????????????,?«???»«??????»??,?????????????????????,?????????????????,????????????,???????????,??

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????Aradhana Sarin??,????????????,?,?????

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