??????????11???????????????????????????10?????(?? ??????????????????)?????????????????113??????????;????????????14.1????;????????:??;?????????FDA?;????;?????????????????????????????????KRAS G12C????????;??????????????;??????????……????11??4?????????-11???10??????????,???????

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11??????5?????????????,?,?,???“??”??????????????????????“????”???????,???????????????????????????,????????????,???????????????????

??????????????:????113???

11????7??????,??????,?????????40????????????????,?????“?”????30??,????,113???????????????????????????????????«??????????????????????(ICD-11)»?,?????????,??????????????????????,?ISO/TC249,?????113?????????????????

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11????????????????????????7??????????????,????App???????,??????????????,??,?????????????2.1????????14.1????????????????????????,?571%??????????????????????????????????2022??????????4???????,????,????????????????????????(????????)????????????????,?????????????(600436)?????????????

?????????:?????????????

11????8??????????????????????,??,??????????????????????HRS-2189?????????????HRS-5041 ????HRS-1358??????????????????HRS-8080??SHR-8068?????????????????????????????????????HRS-620 ?????????????????????????????????????????«??»,??

???FDA????????????????????????

11??????????????????8????????,???????????????????,???(FDA)????????????????(New Drug Application,NDA),?????,??? FDA ?????????????,?(EGFR)20 ?(Exon20ins)????(NSCLC)???????????? FDA ????????????

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??????

11????????6?,??????????,???????????????????®(?)????,??????????????(ANCA)???????(????[GPA]?[MPA])?????

?KRAS G12C??????????????????

11??????????????9?????????????????,????,????????KRAS G12C?????????????(????????????????????????“??????????????????”)????????????,???KRAS G12C?(NSCLC)???????,???,????????????1?????????????????????????????,???????????????????????????5???,??????????????????????6????????????????????????????KRAS G12C??????????,??????????????????KRAS G12C???????????????

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11???????????????????7???????????,??????????«????????????????????????»?«?»??????,?,???,???????????«??»«???????????»?,????????????,??????,????,????????????????????,?????

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??????Aradhana Sarin??????,??????,??????????????,?????????????

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11??????5?????????????,?,?,???“??”??????????????????????“????”???????,???????????????????????????,????????????,???????????????????

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11????7??????,??????,?????????40????????????????,?????“?”????30??,????,113???????????????????????????????????«??????????????????????(ICD-11)»?,?????????,??????????????????????,?ISO/TC249,?????113?????????????????

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11????????????????????????7??????????????,????App???????,??????????????,??,?????????????2.1????????14.1????????????????????????,?571%??????????????????????????????????2022??????????4???????,????,????????????????????????(????????)????????????????,?????????????(600436)?????????????

?????????:?????????????

11????8??????????????????????,??,??????????????????????HRS-2189?????????????HRS-5041 ????HRS-1358??????????????????HRS-8080??SHR-8068?????????????????????????????????????HRS-620 ?????????????????????????????????????????«??»,??

???FDA????????????????????????

11??????????????????8????????,???????????????????,???(FDA)????????????????(New Drug Application,NDA),?????,??? FDA ?????????????,?(EGFR)20 ?(Exon20ins)????(NSCLC)???????????? FDA ????????????

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11????????6?,??????????,???????????????????®(?)????,??????????????(ANCA)???????(????[GPA]?[MPA])?????

?KRAS G12C??????????????????

11??????????????9?????????????????,????,????????KRAS G12C?????????????(????????????????????????“??????????????????”)????????????,???KRAS G12C?(NSCLC)???????,???,????????????1?????????????????????????????,???????????????????????????5???,??????????????????????6????????????????????????????KRAS G12C??????????,??????????????????KRAS G12C???????????????

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??????Aradhana Sarin??????,??????,??????????????,?????????????

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