????:1???????:??????

2?????????

3???????????

4??????????

5????????

??????????????9????????30??? (? ?)????????9????????????????????????????,?????“?????”,?????????40%?

????5??“????????????????????”,????????????????“????????”???????????,??????,?????????,???

?????,?????????????????,?????????,???????????,??????

?????????,???????????????63????????????,60????????70?????????,????????,???????????????,???1%?????????,???????B??????

?????????????????,??????????????“70%”:70%???????;70%??????;??70%???????5???

“????70%??????:???????????????????????????”??????????30?????,??,“?????????,????????????70%70%??”?

??????????,??????????????????????????????“????????????,??????????,???????????????????,???????????????????,??????????????,??????”???????,????,??????????????????????,?????????,??10%????5???

??,?????????????PARP??????????,????????????????“????????”,??????????????????????

???,??????????????????“?????,???????,???????????,??????,????????????????,?????????????????????????,?????????????7???????????,????????????????,?????”?(???????????) ????:????????