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????:??????200:????

????????11???????10?????(??????????? ??????????????????)???????113????????????;??????????????????????14.1??????;????:?;???FDA?????;???;?KRAS G12C??;??????????;????……?11????4?????????????????????????????????-11???????????????????10??????????????,??????????????????

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11????????5?,??????,???????????????????????????,?“???????????”????????????????“???????????”????????,????,????,??????????????????????

????????????:?????113??????????

11????????????????????????7?????????????????,?,??????????????40????????????,??“??”??????????????????30?,?,113?????????????«?????????????(ICD-11)»????,??????????????????????????????????????,?????????????,????????ISO/TC249,???????????????????113??????????????

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????????14.1????

11?????????????7??????????????????????????,?App????,????,?,???????????2.1?????????????????14.1????????,?571%???????????2022????????????4?,?,??????????????????????????(?????????)????,??????????(600436)??

??????:??????

11?8???????????,????????,??????????????????????????HRS-2189????????????????HRS-5041 ??????????HRS-1358????????????????HRS-8080?????SHR-8068???????????????HRS-620 ????«??????????????????????»,???????????????

??????FDA???

11?????????????????8??,???,????????????????????????(FDA)???????????(New Drug Application,NDA),????????????,???????????????? FDA ???????????????,????(EGFR)20 ?(Exon20ins)??????????????(NSCLC)??????????? FDA ????????????????????????????

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11?????????????6???,??,????????®(???????????)???????,??????????????????????????(ANCA)??(????????????[GPA]????[MPA])??

????????????????KRAS G12C???

11????????????????9????????????????,?,??KRAS G12C???(??“?”)????????????,??????????????????KRAS G12C?????????(NSCLC)????,????????????????,????1?????????????????,??5?,??????????6????????????????????KRAS G12C????????????,??????????????KRAS G12C??

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11????????????????????????7??,?????????«????»?«???????????????????????????»??????????????,???,????????????????????,??????«?????????»«??????»????,???????????????????????????????????,?????????????????????????????,??????????,???????????????,??

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??????Aradhana Sarin????????,??????????????,???????,?????????

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