????:1????????????:??????

2?????????

3???????

4???????????

5?????spa

??9???30??(????????? ????????? ?????? ????? ??????????)????,???????????????????????????,???,??,??????????????700??????????

??????????,A???????????:???????????????????,?????????????,?????????????;??,?????????,??????,?????;?????????????,????????????????“??????”?

??

??,???????????9??????????????????,??????????????18????????????????

??

9??????????23?????,?????????????????????,???????????????????????????,?????????????????,???????,????????????????

??????????????????,?????,???????????????4??,?????????9?????,?????????????

???,??????????????????,9???????????14???,?????,?,?????????????????????????????????3????????????,?????????????????????????????,??????????????9???????????????7????,?,???

  ??????????,???9????????,??18???????(????????:????????? ??????????? ????????????)

?????????????????????

?????????????????,?????,??

??,????,????ADC?mRNA?????????????,??????2024??????,??????????????????,??????????27.71%,?? ????65.87%,????????277.60%?

?,???9???“????????????????????????”?????????????,??,?????TSLP?OX40(CD134)???????(pDCs)??,?????,??????????????????????????????????

????????????????????9??????13??????????????????????????,???,????????????????????????????????????????????????????

???????,?,???????????????2023???,???????????????????2022????????????????????647?????2023???????562??,?13.14%?

????,????????,??????????????????,??,??????????????????????????,?????????????????????2024????10%?????????

“?????????????????”??

??????????,??,??“?????”??????????,??,???????????

9???????????25???????????????????,??????????????????,?????,?????,??????????????,??,??????

??????????,?????????????????,???????????1989??????????????????????,??????????????????????????????????(MIT)?,??????????,3M???(3MUSA)?????????,?????????

2017????????,?????????????,?????????????????????

???,?????????????????????,2023???,???79.80????,???24.78%;???12.58??????????????????,?????????????????42.91%???????2024?,??21.33%;???????????????27.48%?

???????????“???????”????????????????????????9?20???????,???????????????,???????????,??

??????????????????????????,?????????????????1980????????,????????????,????????????,????????????????????(???????????)????????????????????????????????

?????????,??????????HPV?,?????????????????HPV???????????,????????????????????,????????????????

??????“???”????????????,??????????????????????,????????????????,??,?????(????)

????:??