????:1?????:?????????

2????????

3???????

4????????

5???????

???????10?????????????29?????? ???????(??????????????“???????????”)??????(??“??”)29???????,?????RNA??????????,?????????????,??????????????

?????????????????????4????????,????39??????,?????????????????????150?????????20???????

???????????????????:????????(AI)???????????????????RNA??,??????;?????????????,???????;???CpG-LNPs?????,??????????????????????(RSV)mRNA???????;????????????,??(DMAP)??,??????????????????;?????????????????mRNA???????????????????????;??????3D?????????,???

?????,???????????????,??????RNA????????????????????????,?????????,????????????,??????????????(??????????????????????) ?????????????????????:?????????