???? “???”?????????????

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????????????9??????????????30???????????????????????(?????? ?? ?? ???? ??????????????????????????????????)??????????????,?????????,????????,?,????700?????????????????

???????????,A????????:???????????????,??????,?;?????,????,???,??????????????????????????;??,??????????“??”?

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??,????????9?????????????,???18?????????

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9??23?????,????????,????????????????????????,???????????????,???????,??

???????????????,?????????????????????,????????4??,???????????9??????,?????????

???????????????????,?????,9?????14???????????,????,??????????????????,????????????????3????,????????????,???????????????????9?7?????????,?????,???

  ??,?????9?,??????????????????18????????????(???:????????? ??????????????? ????)

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?????????,??????,???

??????,??????????,???ADC?mRNA?,???????2024??????????????,???????????????????????????,???????????27.71%,??????????? ??????65.87%,???????????????277.60%?

??,?9????????“???????”?????????,???,??????????????????TSLP?OX40(CD134)?????(pDCs)?????????????????????,???????????????,????????????????????????????

????????????????????9??????????????????13???????????,??????????,????????????????????????????????????????

???,?????????????,?????????????????????2023?????????????????????,???2022?????????????647????????????2023?????????????562??????????,???????????????????13.14%?

???,?????,????????????????,????????,??????????,?2024?10%?????????

“???”?????????????????

??,??,???????????“?????”????????,?????????????,??????????

9??????????25??,??????????????????????????,??????????????,??,?????,??????????????,???????????????????????

???,?????????????????????????????????????,????????????????????1989???,??????????????(MIT)??????,??????????????,3M??(3MUSA)????????????,???

2017?????????,??????????????,??????????????????????????????????????????????????????

?????,??????????,2023?????????,?79.80?????,??????24.78%;??????????12.58?????????,???????????????42.91%??2024?,??????????????21.33%;???27.48%?

????????“???”???9????????????????????20???????,?????????????,????????????,?????

????????????,????????????????1980?????,??????,???????????,?????(??)???????????????????????????

?????????????????,?????????????????????HPV???????????,??HPV??????????????,??????????,?????

??????“?????????????”??????????????????,?????????????,????????????,????????????????????????,????(??????????)

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