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???2025????2?????????????????????????????????????21????,?«?????????????»?????????“Base-modified nucleotides mediate immune signaling in bacteria(????????????????????????????)”?????????(??)????????????,?????????????“????????????”(Kongming),?????????????“??????”????,???????????
???????????,???????????????????????????????,??????????????????“?????????????????????”???1950????(????????????cAMP?cGMP)??????????????????,????,?????,???????????????,??,??????KomA(?A)?KomB(????????????????????B)?KomC(??????C)??????????????????????,???????(DNK)???????????“????”:KomA???????????DNK???,??????(dAMP)??dITP???KomC??NAD⁺,??????????“???????????”????????,???,???????????????“?????”????,?????????????????“?????????”??,???????
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