?? ??|???????,“???????”?????
????:1?????????:???????
2???????????
3?????????
4?????????
5??????
?,??????????????CAR-T(????T??????????????????)????????????????????????“?????????????????????????”???????????
CAR-T????,???????????:?????????????,???????????????“????????”?????????????“??????????????????????,????”??,???????,?????????????
???“??????????”,????????????
????? 11 ?????????????????????????,???????,99.9????????????????CAR-T???????????,??CAR-T???????????????????????????????????1?????,???????CAR-T????????????????,????,??????120??CAR-T?????60????????????
8?????,???????????,????CAR-T????????????6???????????????????????CAR-T????????“????????????”?????,??,?????“??”??,???????“????????”????“?”????????????????,???
??????????,????????????????:???????????????????“??”??????????“???????”????,??????????CAR-T????????“????????????????????”?????????,???
???????,???????“??????????”?????????????,???????????????????,CAR-T???????,?????????
????????????
???????????????70%???????????60%????????????????????,???????????“????????????????????????”?????????????????41.3%?
????,????????????????????,??“???????????”??????????????,????,???????“?????????”,??,????????
??CAR-T?,“??”????????
??®(????)?????????????,????????2021??,???????,??????????,???
?????????“???????????????”???????????????????????????,?8????????,???????????????,????????????/?????????????????????,?????????????,?????4?????????????CAR-T?????????????????
????,???????????????????????,????????????29??????????????????????,?????30???????????????,???99.9????????????????/????~120???/????CAR-T?????,???????
??4????????,??????,????????????????,??????????????,???????,???CAR-T????????????????????????????,?????????CAR-T?????
???????????,CAR-T??????,???????“??”,??????????“????????????????????”??????????????,????????????????????????CAR-T????????????????????????,?????????
????????,?,???????
????????«?»?????,???,???“?????????”?????????????,???“??”??????,?????????????????????????????????
??????????,CAR-T????,???????????:
????,CAR-T??100???????????????,?????????????“????”???????????2023????????????1.9??????????????????????????(19.4%)????1.7?????(25.3%),??????????????????????????????,???“?”?????,???????“?????????30??????”??,????????“???????????????????????????”?
????????????????,???,??????????????????????????????,???????,??????????CAR-T??????,????????,????????,?????????????????????????????????,???“??????”????????????
???
?,?????????????????CAR-T???,??????????????????“???????????????????????????,?”???????,????????????????“???”?????????
??????????????,??????????????????????????????????????????,????????????CAR-T?????????,?????
??1??????????????????,??????????????“????????”,???????,????????????60????????
?????2024?????????,??????,??,??????????????????,???,???
??:“??????????????,???????????????,??????????????????????????????????????”
????????,??????,??,??“??????”,??,????????????????????????,??????????????,?????????,??????????????????,??????,???????????????????????????
?????????????,???????????“1+3+N”???,????“N”????????????????????,?????????,?“N”?????,????
?????????????,????
??“????????????”???,?????????????????,??????????????????
??,??,???,????,??
“??,?????????????????????300??????????,?????????????????????CAR-T??????????,CAR-T?????????????????,??,?????????,???????‘????????’???????,??,???,??,???????,??,???????;??,????????????,??,??‘??’?”??????
????“???”??????????,????,??????????????????????????
????????????????????,??????????????,??????????,???????,???,????????????50??????????,???????,???????????,?????????????????
??????????????,??????,????????????,?????????????????????????????????????????????,????
???,?????????????,????????????,?????“?????????”,??????????,????????????????????????????????????????????????????,??????????
???,???????????????????,?????????????,???
?????????????????“??????????”,????????????????????,????????????????????????????????
????100???????CAR-T????????,???????,????????????????????,???????????????????????????????,??????????CAR-T?26???????,??,???????????4?????????,?????????
?“?”,??,???????????,???
“???100??????????????????,?????CAR-T??????????,???????????,?????????????????????,???????????????????????,???????????”?????????,????????????????,??;???????????????????;?????????????????????,????,??????
CAR-T?
?????CAR-T?????????,???:CAR-T????????????????????????????CAR-T???????
??CAR-T???,?????????????,???????,??????????????????CAR-T??,????????????????????,??????
?????,??“???????”????,?????,?????,????“?????????”??????,??????????,?????????????????????????????CAR-T????????????,??,????????????????
???????????????,CAR-T???????????????????,??????DRG/DIP???,??????????????“??”??????,??????????“??????????,???????????,????????????”????????
???,“?????????????????????”???????????????,?????“??”??????????????????????????,??CAR-T?????
“??????CAR-T?????50%~70%?????”??????????????????CAR-T????????
???????,??????CAR-T????,?????????????????????????????,????,??????????????CAR-T???????????4.3?????,????CAR-T???
?????????,????????,CAR-T??,?????,??????CAR-T?????????????????
?????????????CAR-T????,??????PD-1?????????????????,CAR-T???????,????,???????????,???,???,??,?????????
?????2024??3????????1??????????CAR-T????????????(????????????)?????,????????????????? CAR-T??11 ???,??6???????????
?????“2025-2030????????(CGT)??????????????????”????????,??,??????????????????CAR-T?????????????,2023???????20%,??184??????,???????168???????????????????
?????????????????,???,??????????CAR-T??????“????”????????????????????
?,2032???CAR-T?885.2??????????????????????????????????????????????,????????“?????????????,???????????”(?? ????????????????:??) ????????????????:??