???????2025??????2??????21??,??«??»??“Base-modified nucleotides mediate immune signaling in bacteria(??)”?????????????????????(??????????????????)????,????????????????????“?????????????????????????????????????”(Kongming),??????????“?????????????????”??,???????????????????
???????,???????????????????,??“??????”???1950?????????????????????(??????cAMP?cGMP)????,??????????????????,??????????????,??????????????????????????????,????????????,??KomA(??A)?KomB(?B)?KomC(???C)??????????????????????????????,?????????????????(DNK)??????????“???????”:KomA???????????DNK?????????????,??(dAMP)????dITP????????????KomC????NAD⁺,????“?”????????,????,??????“??”?????????,????????????“???????????????”??,???
?,“??????????”?????????,???(??????KomB-KomC???????????KomA)???????????????????????????????????????,???dITP????:???????????,????????????????????????????(?????????????ADA????)????,????
(?????? ???? ???) ??????:??
?????????????:????????
????K?!??????!????????
?S??????????????????
??6??????????????????
?????????:??????1.5%??????…
YG?????????????????????
??CEO??:???????C2C?????
??31??????????23??????
IDG????????:????????
???????????!????????
YG?????????????????????
????????“??”????????
?????????????????????
??????????????:??????????
????????????????5???
???????????????5???
??????????????????34??
????????????????????
?????????7???????????????
«??»??90?????,?21????
???:????????5???????????
??????????“???”?????????
?????????:??????1.5%??????…
?????????????????????
???????????:??????????120%