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??,?????????????????????????????,????????,????:?????????????????????????????????????,????????????,??20%??????30%??????????,??????:??????????“?,???????”?????,?,?????????????????

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???????,?????????????????-2(HER2)?????,??????“HER2??????”???????????????????“HER2?????????????”????????????????????????????????,?????HER2??????????,??????HER2???????????????,HER2?????????

?????????????,??????,HER2????20%????????????????,???,?????,ADC??????????????????“HER2??????HER2??????????,????????????????????ADC????,??????????,???????????HER2??????,ADC???,?????‘1+1>2’???,????????”

HER2?????????????45%??55%??,??????HER2??????????????,??HER2?????????????????,????HER2??????????????????:“?????HER2?????????????????????,??????????ADC?????????????HER2???HER2??,?????????????????,????????????HER2?????,???,?????????”

????????????,ADC????,???????????????,ADC??????????;???????

??????????????,??????????????????2017????????????????,???,?,?????????????,??????????????:“?????????????????,????????????,????????”

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