????:1??????:???????

2?????????????

3????????

4????????

5???????????

???????????????????2????????????????8???????????? (????? ??)8??????,?:???????????????????????,?????????????T2T??????--?????????????????????,??????“?????”??????????????????????

??,??,????,??,??????,??,?????ONT?Hi-C?????????,?????????????????T2T???????????,??“?????”,????????

??:????????????????????????,?????????2.66Gb??,?N50???Scrofa11.1??????????????,???,????????1-12????????????????????????????X????,?13-18?????????????????,????????

?:???????????????????T2T?????????,?????????,????????????194,234???(SV),????SV????????????????????????????????,??????????

?????:??????????????????????T2T??????,?89?????????,?????????????????????TPT1??????????????????????????????????SV???RNA?????????????,?????17?????????????????????????

???:??????????????????????????????SV??,?????(GS)???????????,6????????5?????70%,???????????????????88%????????????????,80%??????“SNP+SV”?????,????????????????2%-4%?????????????????????????,???????CL3??SV??????????,???????????

??????,?????????????:???????????????????;SV???,?????????????????,????????????????????;??,?????????????,?????(????????????????) ???:???