????????????????????,????CAR-T(???????????T????????)????????“????????????”????????????

CAR-T???????,?????:??,?????????“??????????”?????????“?,?????????????”?????????????????,???????????????????????????????,??????

????????????????“???????????”,??????????

????????????????? 11 ???????????,??,99.9?CAR-T???????????????,????CAR-T?????????????1????????????????,???????????????????CAR-T????,????????????,?????120????????????????CAR-T???????????60???????????????

8??????,????????,????CAR-T???????????6?????????????????????CAR-T?????????????“?”??,?????,???????“????????????????????”????,?????????????????“??”???????“??”??????,??????????????????????

?,???????????????????????????:????????“??”????“??”???????,???????CAR-T???????“???????”????????????????,????????

????,?????????“??????????”??????????????????????????,?????????????????????,CAR-T????????????????????????,???

?????????????????

?????70%?????60%?????????????,?????????“??????????”?????41.3%?

??????????,?,?????????“?????”?????????????????,??????????,??????“??????????”,???????,??????

??CAR-T???????,“???????????????”????

???????®(????????????????????)???,??????????????????2021?,????????,???,??????????

????????“????????????????”??????,?????8??????????,???????????????,??????????/???,???????????,???4??????????????????????????????CAR-T???????????????

????????????????,??,????????????????????29????????????,??????????????????30???????????????,????99.9???/????????????~120??????/??????????CAR-T?????????,???????

????4??????,??????????,???????????????????,?????,?????,??????CAR-T???????????????????,??CAR-T?????????

??,CAR-T????????????,???????????“?????????????????????”,???“????????????????”??,??????????????????CAR-T????????????,??????????

??,?????????????,???

???????«?????????????????»?,????????????,????“???????????????”??????,??????????“??”?????????????,???????????????????????????????????????????????????

????????,CAR-T??????????,???:

??????????,CAR-T???????100???????????,??“??????”?????????????????2023?????1.9??????????????(19.4%)??1.7?????(25.3%),??????????????????????,??????“??????”?????????????????????????,??“?????????????30?????????”???????????,????“???????????”?

?,???????,??????,???????,?????????????CAR-T??,???????????,??????,????????????????????????,????“???????????????????????”????????

??????????????????

???,?CAR-T???????????????,????“???,????????”??????????????????,??“??”????????

??????,??????????????????????????,????????????????????CAR-T???,??????

????????1????,??????????“?????”,??,????????60??

??????????????????????????2024??,??,?????,??????????????,?????????,???

???:“?????,???????,????????”

?????,???????????????????????????,?????,??“??”,?????????????,??,?????????,??????????,???????????,???????,??

???????,????“1+3+N”???????????,??“N”??????,?????????????,????????????“N”?????????,????

???,???

?“??”???????,?????????????????,???????????

???????,????,?????????????????,??,???

“?????????,????????????????????300?????????,?????????????????????????CAR-T??????????????????????????,CAR-T????????????????????????,???????????????????,??????????????????,???‘???’?????????,??????????????,??,??????????????,????,??????????,???????????;???,??????????????,??,??????????????????????‘??’?”??????????????????????

??“???????”??????????,?????????????????????,?????????????????????????

???,??,?????????????????????????????,??,?????????????,?????????????50????????,????????,????????,??????????

???,?,??????????????,????????????????????????????????????????,???????

??????????,?????,?????????????????????????,?????“????????????”,?????,??????????????????????,????

????????,??????????,??????????????????,???

?????????“???????”,???????????????,???????

?????????????????????100??????CAR-T?,??????????,????????????????????,?????????????????????????????,???????????????CAR-T??26???????,?,???????????4??????????????,?????????????????????

??“????”,??????????????,?????,????

“????????????100??????????????,????CAR-T???,????????,???????????????????,?????????????????????????????????????????,?????????”??????,??????????,??????????;??????????????????;??,???,?????

CAR-T?????

??CAR-T???,?:CAR-T???????????????????????????CAR-T?????????

?????????????CAR-T?????????????,?,???????????????,?CAR-T?????,???????????????????????????,??????

??????????,??????????????“???”???,????????????,??????????,??????????“??????”??????????????,???????,???????????????????????????????????CAR-T?,??????????????,???????

??,CAR-T???????????,?????????DRG/DIP????????,???????????????“??”????????????????????????????,???????????“??,???,????????”???

??????,“?????????????????????”????,????????“??”?????????????,?CAR-T????

“???????????CAR-T?????50%~70%?????”????CAR-T?????

?????,???????????CAR-T?????????????????,??????????????????,????,???????????????CAR-T???????4.3??,??????????????CAR-T???????????

??,??????????,CAR-T???????????????,????????????????????????,???CAR-T???????????????????????

?????????CAR-T???????????????????????????,????????????PD-1???????,CAR-T???,???????????,???????,?????,?????,???????????????????,???

?????????????????????????2024???????????????3?????1?????????????????????CAR-T?(????????????????)????????,?? CAR-T????11 ????????????????,???6???

????????????“2025-2030???(CGT)???”????????,??????,??CAR-T????????????????????????????????,2023??????????????20%,????184???,??????168???????????????????

????????,??,???CAR-T????“??????”?????????

???,2032???????????????CAR-T??????????????885.2??????????????,?????????“????,??????????????????????????????????????”(??????????????????? ???:??????) ??????????????:??????? “?????????”_????

?? ???????|???????,“??”?????

????:1??????????:??????

2????????

3?????VX

4????????

5???????????

????????????????????,????CAR-T(???????????T????????)????????“????????????”????????????

CAR-T???????,?????:??,?????????“??????????”?????????“?,?????????????”?????????????????,???????????????????????????????,??????

????????????????“???????????”,??????????

????????????????? 11 ???????????,??,99.9?CAR-T???????????????,????CAR-T?????????????1????????????????,???????????????????CAR-T????,????????????,?????120????????????????CAR-T???????????60???????????????

8??????,????????,????CAR-T???????????6?????????????????????CAR-T?????????????“?”??,?????,???????“????????????????????”????,?????????????????“??”???????“??”??????,??????????????????????

?,???????????????????????????:????????“??”????“??”???????,???????CAR-T???????“???????”????????????????,????????

????,?????????“??????????”??????????????????????????,?????????????????????,CAR-T????????????????????????,???

?????????????????

?????70%?????60%?????????????,?????????“??????????”?????41.3%?

??????????,?,?????????“?????”?????????????????,??????????,??????“??????????”,???????,??????

??CAR-T???????,“???????????????”????

???????®(????????????????????)???,??????????????????2021?,????????,???,??????????

????????“????????????????”??????,?????8??????????,???????????????,??????????/???,???????????,???4??????????????????????????????CAR-T???????????????

????????????????,??,????????????????????29????????????,??????????????????30???????????????,????99.9???/????????????~120??????/??????????CAR-T?????????,???????

????4??????,??????????,???????????????????,?????,?????,??????CAR-T???????????????????,??CAR-T?????????

??,CAR-T????????????,???????????“?????????????????????”,???“????????????????”??,??????????????????CAR-T????????????,??????????

??,?????????????,???

???????«?????????????????»?,????????????,????“???????????????”??????,??????????“??”?????????????,???????????????????????????????????????????????????

????????,CAR-T??????????,???:

??????????,CAR-T???????100???????????,??“??????”?????????????????2023?????1.9??????????????(19.4%)??1.7?????(25.3%),??????????????????????,??????“??????”?????????????????????????,??“?????????????30?????????”???????????,????“???????????”?

?,???????,??????,???????,?????????????CAR-T??,???????????,??????,????????????????????????,????“???????????????????????”????????

??????????????????

???,?CAR-T???????????????,????“???,????????”??????????????????,??“??”????????

??????,??????????????????????????,????????????????????CAR-T???,??????

????????1????,??????????“?????”,??,????????60??

??????????????????????????2024??,??,?????,??????????????,?????????,???

???:“?????,???????,????????”

?????,???????????????????????????,?????,??“??”,?????????????,??,?????????,??????????,???????????,???????,??

???????,????“1+3+N”???????????,??“N”??????,?????????????,????????????“N”?????????,????

???,???

?“??”???????,?????????????????,???????????

???????,????,?????????????????,??,???

“?????????,????????????????????300?????????,?????????????????????????CAR-T??????????????????????????,CAR-T????????????????????????,???????????????????,??????????????????,???‘???’?????????,??????????????,??,??????????????,????,??????????,???????????;???,??????????????,??,??????????????????????‘??’?”??????????????????????

??“???????”??????????,?????????????????????,?????????????????????????

???,??,?????????????????????????????,??,?????????????,?????????????50????????,????????,????????,??????????

???,?,??????????????,????????????????????????????????????????,???????

??????????,?????,?????????????????????????,?????“????????????”,?????,??????????????????????,????

????????,??????????,??????????????????,???

?????????“???????”,???????????????,???????

?????????????????????100??????CAR-T?,??????????,????????????????????,?????????????????????????????,???????????????CAR-T??26???????,?,???????????4??????????????,?????????????????????

??“????”,??????????????,?????,????

“????????????100??????????????,????CAR-T???,????????,???????????????????,?????????????????????????????????????????,?????????”??????,??????????,??????????;??????????????????;??,???,?????

CAR-T?????

??CAR-T???,?:CAR-T???????????????????????????CAR-T?????????

?????????????CAR-T?????????????,?,???????????????,?CAR-T?????,???????????????????????????,??????

??????????,??????????????“???”???,????????????,??????????,??????????“??????”??????????????,???????,???????????????????????????????????CAR-T?,??????????????,???????

??,CAR-T???????????,?????????DRG/DIP????????,???????????????“??”????????????????????????????,???????????“??,???,????????”???

??????,“?????????????????????”????,????????“??”?????????????,?CAR-T????

“???????????CAR-T?????50%~70%?????”????CAR-T?????

?????,???????????CAR-T?????????????????,??????????????????,????,???????????????CAR-T???????4.3??,??????????????CAR-T???????????

??,??????????,CAR-T???????????????,????????????????????????,???CAR-T???????????????????????

?????????CAR-T???????????????????????????,????????????PD-1???????,CAR-T???,???????????,???????,?????,?????,???????????????????,???

?????????????????????????2024???????????????3?????1?????????????????????CAR-T?(????????????????)????????,?? CAR-T????11 ????????????????,???6???

????????????“2025-2030???(CGT)???”????????,??????,??CAR-T????????????????????????????????,2023??????????????20%,????184???,??????168???????????????????

????????,??,???CAR-T????“??????”?????????

???,2032???????????????CAR-T??????????????885.2??????????????,?????????“????,??????????????????????????????????????”(??????????????????? ???:??????) ??????????????:???????