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????,?????????,??“????”??1950????????????????????????????(??????cAMP?cGMP)???????,????????????????,???????????????,??????????????,?,???????????KomA(??????A)?KomB(?????????????B)?KomC(??C)????????????????,???????????(DNK)???????????????“????”:KomA??DNK???,???(dAMP)?????????dITP??????????????????????????????????????KomC?????????????????NAD⁺,??????????????????“????”???????????????????????,??,????“???????????”????,?????????????“??”??????????????????,?????

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