????:1?51???????:????????

2???????wx

3???????????

4??????????

5???????????

??,???????????????CAR-T(????????????????????T?????????????????)????????????????????“????????????”???

CAR-T??,??????????:????????????????,?????????“?????”???????????“??????????,??????????????????????????”?,?????????????????????????????????????????????,?????

?????????“????????????”,??

???????????????????? 11 ????????????,??,99.9???????????CAR-T????,?????CAR-T???????????1?,????????????????CAR-T??????????????????,??????,??120?CAR-T??????60???????

8?????????????,?????,??????????CAR-T????????6??????????CAR-T??“???”??,????????,????“?????????????????????”??????????????????,????????“????”?????????“????????”????????????????,???

?????????,??:??“???????????”?????????“?”???,?????CAR-T?????????????????????“?????”??????????????,????

??????,???????????“??”??????,????????????????????????????????,CAR-T?,??????

????

?????????70%????????60%??,????????????“???????????????????????????”???????????41.3%?

????,??????????????????????,???????“???????????”?????????????,??,?????????“???”,??????,????????????

??CAR-T??????????,“??????????????”??????????????

?????????????®(???????????????)???????,????????????????????2021??,?,???????????????,???

????“????????????????”?????????,?????8?????????,??,???????/??,???????????,???4?????????????CAR-T??

???,???????,???????????????29???????????,???????30??????????????????,????????99.9?????????/????~120???????????/?CAR-T??????????????,????????????

???????????????4??????,????????,????????????,?????,?????????????????????????????????,???CAR-T???????????????????????,????CAR-T?????

????,CAR-T?,??“????”,???“??”????????,??????????????????CAR-T??????????????????????????????,??????

???????,??????????,???

???????????«??»??????????,??????,?“???????????????”????,??“??????????”??,???????????????????????

???????,CAR-T??????,????????:

???,CAR-T???????100?,????????????“?????????????”???2023??????????1.9??????(19.4%)???????????1.7??????????????(25.3%),??????????????????????,??????“?????”?????????,???“???????????30?”?????,??????????“??”?

??????????????????,?,???????????????????,???????????,?????????CAR-T??????,??,??????????????????,???????????????????,??“????????”????

????????

????,?????????CAR-T???????????????,??“???,????????????”???,??????????“??”?????

?????????,????????????????????????????????????????????????,??CAR-T?????????,???

?????????????????1??,??“????????”,?????,????????????????60???

?????2024???,??,????,???????????????????????????????????????????,??????,????????

?????????????:“?????????????????????,?????,???”

??,??????????,??????????????,?????????????“???????????????????”,?????????????????????,???????????,????????????????????,???????,?????,???????,????

??????????????,??????????“1+3+N”???????,???????“N”???????,???????????,???“N”??????????,??????????????????

??????????????,?????

???“??????????”?????,??????????????,?????????????

?,????,???????????,??????????,?????

“????????,??300???????,???????CAR-T????????????,CAR-T????????????????????????????????????,?????????????????????,????,???‘???’??????????????????????,???,??,?,?????????,??????????????????????????,????????????;??????????,???????????????,????,???????‘??????’?”?????????

????????????“??”????????,?????????????????????????????,?????????????????????????????????

????????,???????????????????,?????????????,?,???????????????,???50??????,????????????,?????????,????????

??,??,?????????,?????????????????????????????,????????

???,?,????????????????????,??????????????????“???????????”,????,???????????????????????????????????,???

??????????,???????????????????,???????,???????????

????“???????”,??????????,????????????????????????????

?????????????100????????CAR-T??,????????,?????????????????,?????????????????,???????CAR-T??????????????????????????????26????????????????????,????????????????????,??4??????,???????????

?????????????“????????????”,????,?????,?????????????????

“???????????100?????,???????????????CAR-T?,???????????,????????????,??????????????????,???????????????”?????,??????????????,???;????????????????????;????????????????????????,???,????

CAR-T??????????

???CAR-T???,?????:CAR-T??????????????CAR-T????????????

??????????CAR-T????,???????,????????????????,???????CAR-T?????,????????????????,???

????,??“???????????????????”????????????????????????,??????????,??????????????,?????????“???????????????”?????????????????????????,?????????????,??????????????CAR-T??,????????????,??????????????

?????????????????,CAR-T?????,??DRG/DIP?????????????????,????????“??????????”??????????,????????????????“?????????????????????????,?????,??????????????”????

???,“??”?????????,??????????“?????????????”?????????????,?????????????????CAR-T??

“???????CAR-T???50%~70%???????????????????????????”?????????????????????????CAR-T????

??????????,????????????????CAR-T???????,???????????????????????,?,???????CAR-T??????????????????4.3???????????????,????????CAR-T?????????

??,???????,CAR-T???????,????,??CAR-T??

???CAR-T?,??????????????????PD-1????????,CAR-T????????,???????,???????????????????????????,?????????????????????????????????????,???????,????????,?????????

??????????????2024??3??1??????????????????CAR-T????????(????????????????????????????)??,?????????? CAR-T??11 ?,?????6????

???“2025-2030?????????????????(CGT)??”????????????????????????,???????????,???CAR-T???????????????,2023????????????????20%,???????184????,??168????????????????????????

???,????,??CAR-T??????????????“??????”????????

????????????????,2032????CAR-T?????????885.2?????????????????????????????,???????????“??????????????,???????”(????????? ??:??) ?????????????:???????