????:2024-12-09 15:27:30 ??:????
????:?????:?????????
?? (?????????)12?8???????,?,???,????????????????,????????????????????????????,????,???????
????,??????????,?????????????????????????,???????????,??????(AFP)?,?????????????19(CYFRA21-1)??????,???????????????????(CEA)????
??????????,??,????????????,????“???”?????????????,?????????????????????????????????
??????,??,?????????10????????????????????,????
???????,?????????????,????,?????????????50?????????????????????,??????????,???????????????,???????????????????????10%?
????????,?????????,?????,?????????,?????????,??,????????????
??????????12????2????,????????????????????????????????17??,???????11?????????30???????????????,????,??????,??(ProGRP)????????149????????/?????????????????,?????????????40??/?,??????????,????????50????,?????????????????????????,?,????????,?????,??????????????,???????????
“????????,???????????????????,??”???,?,??,??????,?????????????????
? 1
?????“??”
????????????“???”,??????????????????????????????????????,???????“??????????”,???????,??
?????????,????????(????????????????????????????????CA125????????CA19-9???????????????PSA)??,?,?????500??220??????,??127?50??,?????????????????,?“?????”?
?????????????,?????????,????????????????????????????????,????“??”?
????? 2
????????????????
???,??????????,???????????????,????
????????????????,??????????,???????????????????19?????????CT???????,???????????????????????,?“?????”???,????????108??50??,??????19?????155?????50?????,???????????163???????????
???? 3
??????
?,???????????????????“??????”??????????,??,???????????????????????????????????????
???1-3??????,??(TPSA)???(FPSA)??????????????????????????,????????????????????????960?,??2880???,?,????????????????????????,?????????400?????,???1680??,????????
¦ ?????????????????
??91?????????26?
???,2024????????????????????????????????,?,??????91??????????26????????????,?,??
??ADC?PD-1/PD-L1?????PD-1/VEGFA???????????,???????????????HR???/HER2?????????????
????“ADC??”????“????”?????????????,??????????2024???????6?????20?????,??????100mg/???????????8860???????????????6912?????????,?????22%?????????,55kg???????????3?????????????,???6000?????,???10????????
??????????????????????????????????????????????????????????????????????????????????????????,??????????????????????,??????,?????????,?????????????40???????14.9%,???????????????35???????6.5%;???????????????2%,??????
?,?????????????????????????,???????????????50???????,??????13220????????????????/125mg/???6166?????/125mg/????,???????????????53.4%;“??”???????????????????? ????????????:???
????