??????????????????????????,???CAR-T(??????????????????T??)??“?????????????????????”?????????????????????

CAR-T?????,???????????:?????????????,??“??”??????????????????“???,????????????????????”??????,??????????????????????????,????????????????????????????

?????“???????????????????????????”,??????????

??????????????? 11 ????????????????,???????????????,99.9?????????CAR-T??,???????CAR-T???????????????????????????????1?,??CAR-T????????????????????,??,??????????120??CAR-T??????????60?????????????

8?????????????,??????????????,??CAR-T??????????6??????????????????????CAR-T?“???????”?????????????????,?,?????????????“???”??,?????????????????“?????????????????????”????????????“???????????”??????,?????

????,?:??????“??????”????????“??????????”??,???CAR-T?????????“?????????”???????,????

????????????????,????“???????”???????????,????????????,CAR-T??,?????

??

?70%?????????60%??????????,???????????“??????????”??41.3%?

???????????,???????????????,?“???????”????????????,???????,???“?????????????????”,???????,??????????????

???????CAR-T?????????????????,“??”?????????????

?????®(?????)????,??????????????2021??????,????,??????????,???

?“???????”??????????????,?????8???????,???????,??????/???????????????,?????????????????????????????????????,???????????4??????CAR-T?????????

??,???????????,????29???????????,?????30???????????????????,????????????????99.9????????/????~120??????/????????CAR-T???,???

?????????????????4???????????,????????????,???????????????????????????????,?,?????????????????????????????,????????????????CAR-T?????????????,???????????CAR-T??????

?,CAR-T??????????,????????????????????“???????”,???????“?????????”??????????,?????CAR-T???????????????,??????????????????????

????????????????????,????????????????,???????

????????????????«????»???????????,???,??????????????“?????????”?????????????,????????????????????????“?”???????,???????????????????????????

??,CAR-T?,??????????????:

???????????????,CAR-T???????100??????????????????,??????“?????”???????2023????1.9??(19.4%)???????????1.7??(25.3%),????????????????,???????“?”????,??????“????????30?????????????????????”?????????,????????“??”?

????,?,????????,??????????,????????????????????????????CAR-T??????????????????,???,????,???????????,?????“?????”???

???

?????????????????,?CAR-T??,?????“????????????????????,????????”????????????,??“??????????”???

?????????????????????????,?????????????????????????????????????,?CAR-T???????,??????????????????????????????????????

??????1????????,????“???????????????”,??????????,????????????60????

?????2024???????????,?????????????,?,?????,???,???????

???????????????:“?????????????????????????????,?????????,???????????????????????”

?????????,???,??????????,??“??”,????????????????,?????????????????????,???,?????????????????????,??????,??,????

????????,????“1+3+N”?,?????????“N”????????????????????,????????????????,?“N”???????????????????,???????

????????,????????????????????????????

??“???”???????,?????????????????????,?????

???????????????????,????,????????,??,???

“???,????????????????????????300??????????,??CAR-T?????????,CAR-T????????????????????,?????????,????,???‘?’???????????,????????????,??????????,???????????,??????????,??????????????????,????????????;?????????????,??????????????,??,??‘??????????????’?”?????????

??????“???????”?????????,?????????,????????????????????????

????????????,??,????????????????????????,???????,?????????????????,??????????????????????????50???,??,??????????????,??????????????

??????????,???????,???,?????????????????,????????????????????

??,????,?????????????????,????????“???”,???,?????????????????????????????????????????????????????????????????????????,?????????

?????,????????????????,??,??????

?????????????“???????????”,????,????????????????????????

???100??????CAR-T?????????,????????,????????????????,?????????????????,???CAR-T???????????26??????????????????,????????,?4??????????????,?????????????

??“??????”,??????,???????,????????????

“???????????100??????????,??????????CAR-T??????,??,????????????????????,????????????????????????????,?????”???,???????????,???;???????????;????????????,??,????????

CAR-T??????????

?????????????????????????????????????CAR-T???????????????????,?????:CAR-T??????????????????????????????????????????CAR-T???

???????CAR-T???,????,??????????,??CAR-T????????,?????????????,?????????

???????,???“??????”??????????????????,??,????????,???????????“???????”??????????????????????????,????????????,????????????????CAR-T??,??????????????????,???????????????

???????,CAR-T????????????,???DRG/DIP?????????????,????“?????”???????????,???????????????“????,????,???”?????????????

???,“?????”?,?????“???????????????????”???????????,??????????CAR-T?????

“??????????CAR-T??????50%~70%???”??????????CAR-T??????????

???,????CAR-T??,???????????????????,???????,?????????CAR-T???4.3???????????????,???CAR-T???

???????,????,CAR-T??,?????,????????????????CAR-T???????????

???????????????CAR-T??????????????????????????,??PD-1????????,CAR-T??,????????,???????,??????????,????????????????,????????????????,???

?????2024???????????????3????????1?????????????CAR-T???(????)??????,??? CAR-T????????????????????????????11 ???????????,???????6????????

??“2025-2030??????????????????????(CGT)???”????????,???,??????CAR-T??????????????????????????,2023??????????20%,??184???????????,??168??????????????

???,??????,?????CAR-T?????????????????“??”?????

???????,2032?????CAR-T???885.2?????????????,??????????“??????????????????,??????”(?? ?????????????????????:???????) ??????:?????? ??“???????”

?? ???????|???????,“??”?????

????:1????????:?????????

2?????

3???????????

4???????

5???????

??????????????????????????,???CAR-T(??????????????????T??)??“?????????????????????”?????????????????????

CAR-T?????,???????????:?????????????,??“??”??????????????????“???,????????????????????”??????,??????????????????????????,????????????????????????????

?????“???????????????????????????”,??????????

??????????????? 11 ????????????????,???????????????,99.9?????????CAR-T??,???????CAR-T???????????????????????????????1?,??CAR-T????????????????????,??,??????????120??CAR-T??????????60?????????????

8?????????????,??????????????,??CAR-T??????????6??????????????????????CAR-T?“???????”?????????????????,?,?????????????“???”??,?????????????????“?????????????????????”????????????“???????????”??????,?????

????,?:??????“??????”????????“??????????”??,???CAR-T?????????“?????????”???????,????

????????????????,????“???????”???????????,????????????,CAR-T??,?????

??

?70%?????????60%??????????,???????????“??????????”??41.3%?

???????????,???????????????,?“???????”????????????,???????,???“?????????????????”,???????,??????????????

???????CAR-T?????????????????,“??”?????????????

?????®(?????)????,??????????????2021??????,????,??????????,???

?“???????”??????????????,?????8???????,???????,??????/???????????????,?????????????????????????????????????,???????????4??????CAR-T?????????

??,???????????,????29???????????,?????30???????????????????,????????????????99.9????????/????~120??????/????????CAR-T???,???

?????????????????4???????????,????????????,???????????????????????????????,?,?????????????????????????????,????????????????CAR-T?????????????,???????????CAR-T??????

?,CAR-T??????????,????????????????????“???????”,???????“?????????”??????????,?????CAR-T???????????????,??????????????????????

????????????????????,????????????????,???????

????????????????«????»???????????,???,??????????????“?????????”?????????????,????????????????????????“?”???????,???????????????????????????

??,CAR-T?,??????????????:

???????????????,CAR-T???????100??????????????????,??????“?????”???????2023????1.9??(19.4%)???????????1.7??(25.3%),????????????????,???????“?”????,??????“????????30?????????????????????”?????????,????????“??”?

????,?,????????,??????????,????????????????????????????CAR-T??????????????????,???,????,???????????,?????“?????”???

???

?????????????????,?CAR-T??,?????“????????????????????,????????”????????????,??“??????????”???

?????????????????????????,?????????????????????????????????????,?CAR-T???????,??????????????????????????????????????

??????1????????,????“???????????????”,??????????,????????????60????

?????2024???????????,?????????????,?,?????,???,???????

???????????????:“?????????????????????????????,?????????,???????????????????????”

?????????,???,??????????,??“??”,????????????????,?????????????????????,???,?????????????????????,??????,??,????

????????,????“1+3+N”?,?????????“N”????????????????????,????????????????,?“N”???????????????????,???????

????????,????????????????????????????

??“???”???????,?????????????????????,?????

???????????????????,????,????????,??,???

“???,????????????????????????300??????????,??CAR-T?????????,CAR-T????????????????????,?????????,????,???‘?’???????????,????????????,??????????,???????????,??????????,??????????????????,????????????;?????????????,??????????????,??,??‘??????????????’?”?????????

??????“???????”?????????,?????????,????????????????????????

????????????,??,????????????????????????,???????,?????????????????,??????????????????????????50???,??,??????????????,??????????????

??????????,???????,???,?????????????????,????????????????????

??,????,?????????????????,????????“???”,???,?????????????????????????????????????????????????????????????????????????,?????????

?????,????????????????,??,??????

?????????????“???????????”,????,????????????????????????

???100??????CAR-T?????????,????????,????????????????,?????????????????,???CAR-T???????????26??????????????????,????????,?4??????????????,?????????????

??“??????”,??????,???????,????????????

“???????????100??????????,??????????CAR-T??????,??,????????????????????,????????????????????????????,?????”???,???????????,???;???????????;????????????,??,????????

CAR-T??????????

?????????????????????????????????????CAR-T???????????????????,?????:CAR-T??????????????????????????????????????????CAR-T???

???????CAR-T???,????,??????????,??CAR-T????????,?????????????,?????????

???????,???“??????”??????????????????,??,????????,???????????“???????”??????????????????????????,????????????,????????????????CAR-T??,??????????????????,???????????????

???????,CAR-T????????????,???DRG/DIP?????????????,????“?????”???????????,???????????????“????,????,???”?????????????

???,“?????”?,?????“???????????????????”???????????,??????????CAR-T?????

“??????????CAR-T??????50%~70%???”??????????CAR-T??????????

???,????CAR-T??,???????????????????,???????,?????????CAR-T???4.3???????????????,???CAR-T???

???????,????,CAR-T??,?????,????????????????CAR-T???????????

???????????????CAR-T??????????????????????????,??PD-1????????,CAR-T??,????????,???????,??????????,????????????????,????????????????,???

?????2024???????????????3????????1?????????????CAR-T???(????)??????,??? CAR-T????????????????????????????11 ???????????,???????6????????

??“2025-2030??????????????????????(CGT)???”????????,???,??????CAR-T??????????????????????????,2023??????????20%,??184???????????,??168??????????????

???,??????,?????CAR-T?????????????????“??”?????

???????,2032?????CAR-T???885.2?????????????,??????????“??????????????????,??????”(?? ?????????????????????:???????) ??????:??????