?? ???????|???????,“??”?????
????:1????????:?????????
2?????
3???????????
4???????
5???????
??????????????????????????,???CAR-T(??????????????????T??)??“?????????????????????”?????????????????????
CAR-T?????,???????????:?????????????,??“??”??????????????????“???,????????????????????”??????,??????????????????????????,????????????????????????????
?????“???????????????????????????”,??????????
??????????????? 11 ????????????????,???????????????,99.9?????????CAR-T??,???????CAR-T???????????????????????????????1?,??CAR-T????????????????????,??,??????????120??CAR-T??????????60?????????????
8?????????????,??????????????,??CAR-T??????????6??????????????????????CAR-T?“???????”?????????????????,?,?????????????“???”??,?????????????????“?????????????????????”????????????“???????????”??????,?????
????,?:??????“??????”????????“??????????”??,???CAR-T?????????“?????????”???????,????
????????????????,????“???????”???????????,????????????,CAR-T??,?????
??
?70%?????????60%??????????,???????????“??????????”??41.3%?
???????????,???????????????,?“???????”????????????,???????,???“?????????????????”,???????,??????????????
???????CAR-T?????????????????,“??”?????????????
?????®(?????)????,??????????????2021??????,????,??????????,???
?“???????”??????????????,?????8???????,???????,??????/???????????????,?????????????????????????????????????,???????????4??????CAR-T?????????
??,???????????,????29???????????,?????30???????????????????,????????????????99.9????????/????~120??????/????????CAR-T???,???
?????????????????4???????????,????????????,???????????????????????????????,?,?????????????????????????????,????????????????CAR-T?????????????,???????????CAR-T??????
?,CAR-T??????????,????????????????????“???????”,???????“?????????”??????????,?????CAR-T???????????????,??????????????????????
????????????????????,????????????????,???????
????????????????«????»???????????,???,??????????????“?????????”?????????????,????????????????????????“?”???????,???????????????????????????
??,CAR-T?,??????????????:
???????????????,CAR-T???????100??????????????????,??????“?????”???????2023????1.9??(19.4%)???????????1.7??(25.3%),????????????????,???????“?”????,??????“????????30?????????????????????”?????????,????????“??”?
????,?,????????,??????????,????????????????????????????CAR-T??????????????????,???,????,???????????,?????“?????”???
???
?????????????????,?CAR-T??,?????“????????????????????,????????”????????????,??“??????????”???
?????????????????????????,?????????????????????????????????????,?CAR-T???????,??????????????????????????????????????
??????1????????,????“???????????????”,??????????,????????????60????
?????2024???????????,?????????????,?,?????,???,???????
???????????????:“?????????????????????????????,?????????,???????????????????????”
?????????,???,??????????,??“??”,????????????????,?????????????????????,???,?????????????????????,??????,??,????
????????,????“1+3+N”?,?????????“N”????????????????????,????????????????,?“N”???????????????????,???????
????????,????????????????????????????
??“???”???????,?????????????????????,?????
???????????????????,????,????????,??,???
“???,????????????????????????300??????????,??CAR-T?????????,CAR-T????????????????????,?????????,????,???‘?’???????????,????????????,??????????,???????????,??????????,??????????????????,????????????;?????????????,??????????????,??,??‘??????????????’?”?????????
??????“???????”?????????,?????????,????????????????????????
????????????,??,????????????????????????,???????,?????????????????,??????????????????????????50???,??,??????????????,??????????????
??????????,???????,???,?????????????????,????????????????????
??,????,?????????????????,????????“???”,???,?????????????????????????????????????????????????????????????????????????,?????????
?????,????????????????,??,??????
?????????????“???????????”,????,????????????????????????
???100??????CAR-T?????????,????????,????????????????,?????????????????,???CAR-T???????????26??????????????????,????????,?4??????????????,?????????????
??“??????”,??????,???????,????????????
“???????????100??????????,??????????CAR-T??????,??,????????????????????,????????????????????????????,?????”???,???????????,???;???????????;????????????,??,????????
CAR-T??????????
?????????????????????????????????????CAR-T???????????????????,?????:CAR-T??????????????????????????????????????????CAR-T???
???????CAR-T???,????,??????????,??CAR-T????????,?????????????,?????????
???????,???“??????”??????????????????,??,????????,???????????“???????”??????????????????????????,????????????,????????????????CAR-T??,??????????????????,???????????????
???????,CAR-T????????????,???DRG/DIP?????????????,????“?????”???????????,???????????????“????,????,???”?????????????
???,“?????”?,?????“???????????????????”???????????,??????????CAR-T?????
“??????????CAR-T??????50%~70%???”??????????CAR-T??????????
???,????CAR-T??,???????????????????,???????,?????????CAR-T???4.3???????????????,???CAR-T???
???????,????,CAR-T??,?????,????????????????CAR-T???????????
???????????????CAR-T??????????????????????????,??PD-1????????,CAR-T??,????????,???????,??????????,????????????????,????????????????,???
?????2024???????????????3????????1?????????????CAR-T???(????)??????,??? CAR-T????????????????????????????11 ???????????,???????6????????
??“2025-2030??????????????????????(CGT)???”????????,???,??????CAR-T??????????????????????????,2023??????????20%,??184???????????,??168??????????????
???,??????,?????CAR-T?????????????????“??”?????
???????,2032?????CAR-T???885.2?????????????,??????????“??????????????????,??????”(?? ?????????????????????:???????) ??????:??????