????????????????T2T??????

??2?????????????????????8?????? (??? ???????)8???,??:????????????,?????????T2T??--??????,?????????“????????????????”??????????????????

??????????,????,??????????,???,??,??????????????????,???????????ONT?Hi-C?????????????,????????T2T???,???????????????????????“????????????????????”,??????

?:?????????????????????????????????????,?????2.66Gb??,?????N50??Scrofa11.1?????????????????????,?,?????????1-12????X??????,?????????????13-18????????,???

????????????????:????????????????????????T2T????????????????????,????????,???????????194,234????????????????????????(SV),??SV??????????????????,??????

?????????????????:?????????T2T?????,??89????????????????,???????????TPT1??????????????????SV?????????RNA?????,??????17????????????????

??????:????????????????????SV??????????,?????????????????(GS)???????????????????????,6?????????5????????????????????????????70%,?????????????88%??,80%???“SNP+SV”???????????,??????2%-4%????,???????????????????CL3????SV????????,?????

?????,?:?????????;SV????????,?????,?;?????????????????????,???????????????,???????????(?????) ????????????????????:????