??????T2T????????????????

?????2?????????????8????????????? (?????? ???????????????????????)8?????,?????????:?,?????????????????T2T??????????--?????????,???“??????????”???

????????????,???????,????,????????????????,???????,??,??ONT?Hi-C?????,??????????T2T???????????,??????“????”,?????????

?????????????:????????????????????????,??????2.66Gb??,???????????N50????????????????????????Scrofa11.1???????,????????,???1-12?????????????????????X?????,??????????13-18??????,???

?????:????????????????????????????????????????T2T??????,?????,????????????????????????????194,234??????????(SV),????SV?????????????,???

?????????????????:?????T2T???,?89?????????,?????????????????TPT1?????SV???RNA???????????????????????,?????????????17??????????????????????????????????????

??:?????????????????SV???,??(GS)???????????????????????,6?????5?????????????70%,?????88%??????????????????????,80%????????“SNP+SV”??????,????????????2%-4%????????????????????,??CL3????SV????????????????????,?????????

????,?????:????????????????;SV????????,??,???????????????;???????????????,??????,??(???????????) ??????????:????????????????????