????????????????T2T??????

????:????????:?????????????

???2?????????????????????8???????? (???????????????????? ?????????)8??????,????????:????????????????????????????,??T2T??????--??,?????????“?????????????????????”??

??????,?????,????????,??????,?????????,??????,????????????ONT?Hi-C?????,????????????????????T2T?,?????????????“??”,??????????????????

??:????????????????????????????????????????????,???2.66Gb????????,???????????????????N50??Scrofa11.1???????????,???,????1-12?????????????????X?,?????????13-18?????????????????,?????????????

???????:?????????????T2T??????????,??,???194,234?????????????(SV),??????SV????????????????????,???

?:??????????????????????T2T??,????????????89???????,????TPT1??????????????????????????SV????RNA?????,??????????17?????????????????????????????????????????

??:?????????SV?????????????,??????????(GS)????????,6???5?????????70%,??????88%??????????,80%????????????????????????“SNP+SV”????,????2%-4%???????,?????CL3????????????????SV?????????????,???????????

?????????????,??:?????????????;SV??????????,?????????????,?????;?????,????????????????,??????(???????????????) ??????:??????????????????????