????????????????T2T??????

???????2??????8? (??????? ?????????????????????)8?????,????:??????,???????????????????T2T?????--????,????“?????????????????????”???

????????????????,?????????????????,??????????????????,????????,????,???????????????,??ONT?Hi-C?????????????????,?????????????T2T??????,??“?????”,????????

??????:?????????????????????????,?2.66Gb???????????,?????????N50???????????????????????Scrofa11.1????????????????,??????????,??1-12??X???,?????????????13-18??????????,??

?????:????????????????T2T????????????????????,??,???????194,234????????(SV),???????????????????SV??????????????????????????????,??

??????????:????????????????????????????????T2T???????????,???89???????????,??????TPT1???????????????????????SV???RNA?????????????,??????????17?????????????

?????????????????:??????????????????????????????SV??,??(GS)??????????????????????????,6??????5???70%,??88%???????,80%??????“SNP+SV”?????,?????2%-4%????,?????????????????????CL3??SV????????????????????????????,??????

??,????????:????????????;SV?????????????,?????????,?????????;?????????,??,?????????????(????) ?????????????????:?????????