??????T2T????????????????

????:????????:??????

????????????????2?????????????8???? (??? ?????????????????)8???????????,?????????:?????????,???T2T???--?????,??????“??????”???

??????,?????????????????????,??,???????????????,?????,??????????????????,???????ONT?Hi-C???,?????T2T???????????????,?????????“??”,????????

?????????????????:???????????????,??????????2.66Gb?????????????,????????????N50??Scrofa11.1?????????,??,?????1-12???????????????????????X?????????????,????????????????????13-18??????????,??????

???:??????????????T2T??,??,??194,234????????(SV),?????SV????????????????????????????????,??????????

?????:?????????????????T2T?,??89??????????,?????????????TPT1????????????????????????SV??????????RNA??????,??17??????????????????????????????????????????????

????????:???????????????????????????????????SV??????,???(GS)?????????????,6????????????5??????70%,?????????????????????88%?????????????????????????,80%??“SNP+SV”?????????,???????2%-4%?????,?CL3???????????SV?,???????

??,?????:???????????????????????????;SV????,???????????????????,????????????????????????????;??,?????????????????,?????????(?????????????) ??:?????