??????????????,?CAR-T(????????T??)??????????“???????????”??

CAR-T???,???:???????????????,???“??”???????“??????????????,??????????????”??????????,???????????????,??????

??????“????”,???????????????

?? 11 ??,??????,99.9?????CAR-T????????????????????,???????????CAR-T???????????????????1????????????,?????????CAR-T????????????,??????????????,?????120??CAR-T????60??

8??????,???????,?????CAR-T??????????????6????????????????CAR-T???????????“??????????????????????”???????,?,?????“???”???????????????,????“?????????”?????“????????”?????????????,????????????????

?????,???????:?“????????????”??????“???????????????????????”???????,??CAR-T????????“????????????????????????”?????????????????,????????

??????,??“???????”?????????????,???????????????????????????????,CAR-T??????????????,?????

??

?????70%?60%?????????????????,?????????“????”?????????41.3%?

?,???,?????????????????????????????????????“?”?????????????,?,??????????????“?????????????????????”,??????????????????,???????????????????

?????????????CAR-T?????????,“??????”??????????????????

????????????®(??)???????????????????????????,??2021????,???????,?????,????

??????????????????????“??”????,??????????8?????,?????????????,??????????/???????,??????????????,?????4??????????CAR-T???????????

?????,????????,??????29?????????,?30????????????????????????,????????99.9??/??????~120?/?????CAR-T??,?????

???????4??????????,????????,????????,??????,????????????,??CAR-T???????,?CAR-T????

???????????????,CAR-T??????????,??“???????”,???????????“?????”?????????????????,???CAR-T?????????????,????????????????????

????????,????,????????????

????????«??????????»??,???,???“????????????”????????,???????????“??”??,??????????????????????????????????????

????,CAR-T??,??:

??????????????????,CAR-T??????????????100??,??????????????????“?????”??????????2023??1.9??(19.4%)???1.7?????????????????(25.3%),???????????????,???????????“???????????????????”????????????????????,????????“?????30?????”???????,?????“?”?

???????????????,??????????,?????????????,????????,?????????CAR-T?????????,??,??????????????????,???????????????????????????????????????,????????“???????”??

????

????????????,?????????????????????CAR-T????????????????????????,??“????????,??”????????,???????????????????????????“???”???

???,???????????????????????????????,???????????CAR-T????????????,??????????

?????????????1????,????????????????????“??????????”,??,???????60????????????

?????????????????????2024???????????,??,?????????????,????????????????????????????,????????????????,????????

????????:“???????????????????????,???,??????????????????????”

?????????????,??,???????????????,?“????????????????”,????????,??????????,???????????????,??,?????,????,???

??????,???????“1+3+N”???,???????????????????“N”?????????????????????,????????????????????,????????“N”??????,??????????

??????????,???????

??????????“??????????”??????????????????????????,?????????????,?????

?????????????,???????,?????,???????,????????

“??????,??300??????????,?????????????CAR-T????????????????????????,CAR-T???????????????????????,??,??,?????‘??’???????????????,????,???,????,???,???????,?????????????????????????????????????;???????,???????????????????????,??,??????‘???’?”??

?????????????????????“???????????????”????,????????????????????,??????????????????

??,?????????????,????,??,??????????????????,???????????50???,??,????,??????????????????

??,??????????,??,????????????????????????????????????,??????????????????

???????,??????,???????????????????????????,??????????“????????????????”,?,?????????????????????????????????????????????????????,??????????????????????????

??,?????,????????????,?????????

??????????“???”,??,??????????????????

??????????100??????????????????CAR-T????????,????????????????,?????????????????????,????????????????,??????????????????????????CAR-T????????????????????26???,??,????????????????????4???????????,?????????

?“??????????????????????????????”,???????????,?,???

“??????????????????100??,???????????????????????????CAR-T????????????????,??????????????,???????????????????????????????,????????????,??????????????????”?????,??????????????,???;????????????????;????,?????????,??????????????????

CAR-T???

??CAR-T?????????,??????:CAR-T?????????????????CAR-T???????????

???????????????CAR-T????,????????,????????,????CAR-T???????????,??????????????????????????????????????????????,???

?????????????????,??“????????????”??????????,??,?,?????????“?????????”????????????,??????,????????????????CAR-T?????,????,???????????

??????????????,CAR-T???????????,??????????????DRG/DIP???????????,????“??????”???,?????“??,???,???????”??????????????????

?????,“???????????”?,???“?????????”??????????????????,??CAR-T??

“??CAR-T??50%~70%????”????????CAR-T?????

?????????????????????????,???????????CAR-T????,???????????????,???????,?????????????CAR-T?????4.3??,??CAR-T??????

??????,?????????????,CAR-T?????????,??????????????????,???????CAR-T????

????CAR-T?????,???PD-1????????????????,CAR-T???????,????????,??????????????,??????????,????????????,??????,???

??2024??????3?????????????????1???CAR-T???(???)???????????,?????? CAR-T????????11 ???????,????????????????????6?????????

??“2025-2030?????(CGT)?????????”????????????????,???,???CAR-T??????????????,2023????????20%,???????????????184?????????,???168??????????????????

????????,??????????????????????????,?????????????CAR-T???????“????????????????????”???????

??????,2032??CAR-T?????????????885.2???????????,?????????????????“?????????,???????”(?? ??:???????) ?????????????????:??????????????????? “????????”????

?? ?????|???????,“??”???????

????:1?????????:??????????

2???????

3????????

4?????

5???????

??????????????,?CAR-T(????????T??)??????????“???????????”??

CAR-T???,???:???????????????,???“??”???????“??????????????,??????????????”??????????,???????????????,??????

??????“????”,???????????????

?? 11 ??,??????,99.9?????CAR-T????????????????????,???????????CAR-T???????????????????1????????????,?????????CAR-T????????????,??????????????,?????120??CAR-T????60??

8??????,???????,?????CAR-T??????????????6????????????????CAR-T???????????“??????????????????????”???????,?,?????“???”???????????????,????“?????????”?????“????????”?????????????,????????????????

?????,???????:?“????????????”??????“???????????????????????”???????,??CAR-T????????“????????????????????????”?????????????????,????????

??????,??“???????”?????????????,???????????????????????????????,CAR-T??????????????,?????

??

?????70%?60%?????????????????,?????????“????”?????????41.3%?

?,???,?????????????????????????????????????“?”?????????????,?,??????????????“?????????????????????”,??????????????????,???????????????????

?????????????CAR-T?????????,“??????”??????????????????

????????????®(??)???????????????????????????,??2021????,???????,?????,????

??????????????????????“??”????,??????????8?????,?????????????,??????????/???????,??????????????,?????4??????????CAR-T???????????

?????,????????,??????29?????????,?30????????????????????????,????????99.9??/??????~120?/?????CAR-T??,?????

???????4??????????,????????,????????,??????,????????????,??CAR-T???????,?CAR-T????

???????????????,CAR-T??????????,??“???????”,???????????“?????”?????????????????,???CAR-T?????????????,????????????????????

????????,????,????????????

????????«??????????»??,???,???“????????????”????????,???????????“??”??,??????????????????????????????????????

????,CAR-T??,??:

??????????????????,CAR-T??????????????100??,??????????????????“?????”??????????2023??1.9??(19.4%)???1.7?????????????????(25.3%),???????????????,???????????“???????????????????”????????????????????,????????“?????30?????”???????,?????“?”?

???????????????,??????????,?????????????,????????,?????????CAR-T?????????,??,??????????????????,???????????????????????????????????????,????????“???????”??

????

????????????,?????????????????????CAR-T????????????????????????,??“????????,??”????????,???????????????????????????“???”???

???,???????????????????????????????,???????????CAR-T????????????,??????????

?????????????1????,????????????????????“??????????”,??,???????60????????????

?????????????????????2024???????????,??,?????????????,????????????????????????????,????????????????,????????

????????:“???????????????????????,???,??????????????????????”

?????????????,??,???????????????,?“????????????????”,????????,??????????,???????????????,??,?????,????,???

??????,???????“1+3+N”???,???????????????????“N”?????????????????????,????????????????????,????????“N”??????,??????????

??????????,???????

??????????“??????????”??????????????????????????,?????????????,?????

?????????????,???????,?????,???????,????????

“??????,??300??????????,?????????????CAR-T????????????????????????,CAR-T???????????????????????,??,??,?????‘??’???????????????,????,???,????,???,???????,?????????????????????????????????????;???????,???????????????????????,??,??????‘???’?”??

?????????????????????“???????????????”????,????????????????????,??????????????????

??,?????????????,????,??,??????????????????,???????????50???,??,????,??????????????????

??,??????????,??,????????????????????????????????????,??????????????????

???????,??????,???????????????????????????,??????????“????????????????”,?,?????????????????????????????????????????????????????,??????????????????????????

??,?????,????????????,?????????

??????????“???”,??,??????????????????

??????????100??????????????????CAR-T????????,????????????????,?????????????????????,????????????????,??????????????????????????CAR-T????????????????????26???,??,????????????????????4???????????,?????????

?“??????????????????????????????”,???????????,?,???

“??????????????????100??,???????????????????????????CAR-T????????????????,??????????????,???????????????????????????????,????????????,??????????????????”?????,??????????????,???;????????????????;????,?????????,??????????????????

CAR-T???

??CAR-T?????????,??????:CAR-T?????????????????CAR-T???????????

???????????????CAR-T????,????????,????????,????CAR-T???????????,??????????????????????????????????????????????,???

?????????????????,??“????????????”??????????,??,?,?????????“?????????”????????????,??????,????????????????CAR-T?????,????,???????????

??????????????,CAR-T???????????,??????????????DRG/DIP???????????,????“??????”???,?????“??,???,???????”??????????????????

?????,“???????????”?,???“?????????”??????????????????,??CAR-T??

“??CAR-T??50%~70%????”????????CAR-T?????

?????????????????????????,???????????CAR-T????,???????????????,???????,?????????????CAR-T?????4.3??,??CAR-T??????

??????,?????????????,CAR-T?????????,??????????????????,???????CAR-T????

????CAR-T?????,???PD-1????????????????,CAR-T???????,????????,??????????????,??????????,????????????,??????,???

??2024??????3?????????????????1???CAR-T???(???)???????????,?????? CAR-T????????11 ???????,????????????????????6?????????

??“2025-2030?????(CGT)?????????”????????????????,???,???CAR-T??????????????,2023????????20%,???????????????184?????????,???168??????????????????

????????,??????????????????????????,?????????????CAR-T???????“????????????????????”???????

??????,2032??CAR-T?????????????885.2???????????,?????????????????“?????????,???????”(?? ??:???????) ?????????????????:???????????????????