????:1????????:???????

2??????????????

3?????????

4??????????????

5???????100?????

?????????,????????CAR-T(????????????????????T???????)?????“???????????????????????????”????????

CAR-T???????,??????:?????????????????,???“????????”???????“?????????,???”?????????????,??????????????????,????????????

??“??”,?????

?? 11 ??????????,????????,99.9??????CAR-T????,??CAR-T???????????????????????????????????????????????1??,??CAR-T?????????????,????????,??120????????CAR-T????????60??????

8?????????????????????????????????????,??,?????????????????????????CAR-T??6??????????CAR-T????????“????”???,??,???????????????????“?????”??,??????“??????????????”????????“??”???,???

???????,????????????????:????“??????????????”????????????????“????????????????????”???????????,????????????????CAR-T???????????????????????????“??”?????,????????

?,????“????????”??????????????????????????,?????????????????,CAR-T?????????????,????

?????????????????????

???????70%?????????60%??????,?????????????????????“?????????????????”?????41.3%?

???????????????,???,???????“??????”????????????,??,????“?????????????????????”,?????????????????,???

???????????CAR-T??????????????????,“??????????????”??????????????????????????

??????®(?????)????????,??2021??????,???????,?????????????????,??????

??????????????“??????????”??????????????????????,?????8????????,????????,???????????/?????,????????,????4??CAR-T??????????????????????

????????????????,?,????29??????????????????,???????????30?????????????????????,?????99.9??/?????????~120??/?????????CAR-T???????????,????

????4??,????,??????????????????,???????????,??????????????,??????????????????CAR-T???????????????,???????CAR-T???????????????

???????,CAR-T???,???????????“?????”,?????????????????????“??”?,????????CAR-T???????????,???????????

???????????,???,???????????

????????????«????»????,???????????,??????????????????“????????????”????????????????,?????????“??”??,?????????????????????????

??????????????????,CAR-T??????????,??:

??????????,CAR-T???????????????100?,???“??????????”????????????????2023??1.9????(19.4%)?????1.7?????????????(25.3%),????????????????????,??????“?”???????????????????,???????“??30???????”??????????,?“???”?

??,??,?????,?????,?????????????????????CAR-T????????,?,?????????,??????????????????,??????????“?????”???????

?????????

?????,????????CAR-T??,?“?????????,?”????,???????“???????”????

????????????????,??????????????????????????????????????????????????????????????,??????????????CAR-T????????????????????,???????

??????1??,????????“???????????????????????????”,?????????,???60????

??2024?,???????????,??,?????,?,???????

???:“??????????,??????????,???”

??????????,???,????????,??“?????”,?,???,???????????,??,????,??????????,???????

?????,??????????“1+3+N”????????,?“N”????????????,????,???????????“N”??,???????????

?????,???????

???“???????????????????????????”?????????,???????????,?????

???????,?????????????????????,???,?,??

“??,????????????300????????????????????????,?????CAR-T???????,CAR-T??????????????,????????,???????,???????‘???????????’?????,????????,??,?????,???????,??,?;???,???????????????????,?????????????????,????????‘????????????’?”????

????“??”???????????,????????????????????????,????????????????????????

??,???,?????????,???????,????????????????????,???50???????,??????????,????,?????????????????????????????

????????,????????????????????????,??????????,????????????????????????????????????????,????????

??????????,????????????,????????,??“??”,???????????,??????????????????????????????,??????????????

?????,?????????????,??,?????????

???????“??????????”,????,??????????????

?????????100??CAR-T??????????,???,????,???????????????????????????????????,???????????CAR-T???????????????????26???????????,????????,???????????4??????????,???

???????“???????????”,????,???????????????????,???????

“????????????100????,??CAR-T???????,?????????????,?????????????????????????????????,????????????????????????,????????”??????,???????????????????,??;??????????????????????????;????????,????,??????????????????

CAR-T??

??????????????CAR-T?,???????:CAR-T??????????????????CAR-T?????????????????

?????????????CAR-T??????,?????,??????????,??????CAR-T??????????,????????????????????,???????

????????????,???“????????”???????????????,??????,????????????,????????????“????”????????????????????????????,????????????????????????,?????????????????????????CAR-T??,??????????????????????????,?????????????????

????,CAR-T???,????DRG/DIP??????????,??????????“??”????,????“?????????,?????????????,???????????”??????????????????

?,“????”????,?????????“???????”??????????????????????????,?????????CAR-T????????????????

“?????????CAR-T??????????????????50%~70%??????????????”?????????CAR-T??????

????,??????????CAR-T?????????????,??????????????,??,??CAR-T????????????????????4.3????????,?????????????????????????????????????CAR-T??

??,????????????,CAR-T??????????????,????????,?????????????CAR-T?????????????????????

???CAR-T???????????????,??????????????PD-1???,CAR-T??????????????????,?,????????????????????,??????,?????????????,???,??????????????????????

???????????????????2024???????????????3?????????1????????????CAR-T???(??????)??????????????????,??? CAR-T????11 ???????,????????6???

??????????“2025-2030???????????????????????(CGT)????????????????????”?????,??,???????????CAR-T????????????????????????????????????,2023?20%,?????????????????184???????,?????168???????????

????????????,??,?????????CAR-T??“??????????????”??????

???????,2032???????????????CAR-T?????885.2???????????????????,???????????????“??????????????????????????,????????”(????????? ?????????:?) ????????:???????????