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???????2025??2???21?????????????????,????«?????????????????»?????????????????????????????????????“Base-modified nucleotides mediate immune signaling in bacteria(????)”??????????????(??????)??????,?????????????????????“???”(Kongming),?????“??????????????????”??,???
????,????????????????,????“?????????”?????1950????(??cAMP?cGMP)??,???????????????????????,???????????????????????,?????????????????????????,?????,???????????KomA(???????A)?KomB(????????????????????B)?KomC(??????C)??????????????????????????,??????????(DNK)???“??????”:KomA???????????DNK??,???????????????(dAMP)??dITP???KomC??????????????????NAD⁺,?“???”???????????????,?,????“????????????”????,?????????“????”?????????????????????????????,???
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