????:1????????????:??98?

2???????????

3????????

4???????

5????????,??

??8???????????22??????????????????????? (??????????? ??)“KRAS??,????????????????????????‘????????????’??????KRAS G12C???????????????????????????????”???????????

??21???,?????????????????,?????1?(??:????)???????????????????????????,???????????????????????????????(KRAS)G12C?????????(NSCLC)?????????,???????

????,????????????KRAS G12C???????????????,??????????

???,??????,2022??,?106.1???????????????,??80%85%,??????Kirsten??(KRAS)??,????????????????????????????????????????????????KRAS G12C??3%,?????????2.7????????????

??KRAS????????????????????“???????????”,???,??????,?????????40????,?????,?????

????,??????????????KRAS G12C???????????,????????????(?) ??:???????????