??????????????
2025-02-21 15:19:5877936
?????2025???????????2??21??,??????????????????«??»????????????“Base-modified nucleotides mediate immune signaling in bacteria(????)”?????????????(??????)??????,????“??????????”(Kongming),??????????“???????????????????????”???,??
?,??????????????,?????????????“?????????????????????????????????????”???????1950?????????(??cAMP?cGMP)???,???????????????????????????????????????,??????????????????,?????????????????,??????,?????????????KomA(????????????????????A)?KomB(??B)?KomC(????????????????C)????,???????(DNK)????“????”:KomA????????????DNK??????????????????,??(dAMP)????dITP????????????KomC?????????????????NAD⁺,???“??????”?????????????,??,??“????”??????,??“?????????????????”?????,??????????????????????
??????????,“???????????”????????????????????????????,?(?????????KomB-KomC????KomA)???????,????????????dITP??:?,??????(????ADA?????????????????)????,???
(? ??????????? ?) ???????????????????:???????