????|???????????????????

????????2?????????????????????20?????????(??????????)?????????????????????????????????,«?-???????????????????????????»?,????(?????:Ozempic)?????????(????????:Mounjaro)??????????????2?????????????19????,?????,??????

?,2023??,?????2%???????????(semaglutide),??????????????-1????(GLP-1RA),??2????????,???????????9?????????Ozempic?????Mounjaro?????

2????19????,?????????????????,????(NAION)???????????????????,NAION????????????????(????????????????????????????????????????)???????????????????????????????

???????,????????????GLP-1????????,???,???NAION????????????,???????????????????????????NAION??????????????,???????????????????GLP-1RA?????????????????????

????????,??,???«????????????????-?????????????????????»??,??????????9??????????????????,?????????,????????

??,“?????????????,????????,???????,???????????,???”?

???“GLP-1??”??????,??GLP-1??????????????????2017?????,??????????????????????????????????????,???????????????,???

???2024?????,????2018.49?????,??????????????????????????????290???????????,????“????”K????????????????????????????????????????????,?????Ozempic????????2024???1203.42?,?26%;????Rybelsus??????????????????233.01???,???26%;???Wegovy????????582.06????????????????????,????81?,?????86%?

??2024??????,??Mounjaro???????????,?????????115.401???????????,????????????????Mounjaro????Zepbound??????????164.458??

???,GLP-1??????

2023?????????4????????????,????????(??????)???????????????,???????,??????????????????????????????????????????????????????????????????????????????(????) ???????????:????