??????????????
2025-02-21 12:53:4822400
??????2025???????????????2????????????21???????,??????«??»??????“Base-modified nucleotides mediate immune signaling in bacteria(????)”?????????????????????????????????(??)??,??“???????????”(Kongming),????“??????????”????,?????
??,???????????,??“???????????”????????????????????????1950??????(?????????????????????????????????????cAMP?cGMP)??,????????,??????????????,?????????,?????????,??????KomA(???????????A)?KomB(??????B)?KomC(???C)?????,??????????????????(DNK)??????????????????“???”:KomA?DNK?,??(dAMP)????dITP??????????????????????KomC????NAD⁺,???“?”?????????????????????????????????,???,?“?????????????”?,?????????????????“??????”????,?????
??,“??”????????????,?????????????????(??????????????????KomB-KomC???????KomA)????????????????????????????,????????????????dITP????:??????????,?????????????(???????????ADA?????????)?????,??????
(?????????????????? ?? ??) ?????????????????????:??????????????