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??1???????14???? (????????????????? ????????????)“??????????,???????????????,???????”???????????14???????????????,“??????(ADC)????????????????,?,????????,??????????????”

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????,?????????????,????,???????????:?????????????????????????????????,???,????????????????????????????20%???????????30%?????????,?????????????:????????“????,???”?????????????,??????,??????????????????????

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???????????????,?????????-2(HER2)?????????????,???????????“HER2?????”???????????????“HER2??????”?????????????????????,?????????????HER2??,????????????????????HER2?????,HER2??????????????

???????????????????,????????????,HER2????20%??????,??????????????????????,?????????????????????????,ADC??????????????????“HER2????????????????HER2??????,????????????ADC??????,?,???????HER2??????,ADC??,??????????????‘1+1>2’???,???”

HER2??45%???55%???????,??????HER2?????????,?????????????HER2??????????,?????????????HER2????????????????????:“??????HER2??????????,??ADC???????????????????????HER2??????HER2????,???,??????HER2????????????????,??,????????”

?????????????????,ADC?????,????,ADC?????????????????????;????????????????

??,??????????????2017?????????????,?,???????????,??????????????,??????????????:“???,???,???”

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