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??????????????????2025?????2????21??,?«????»????????????“Base-modified nucleotides mediate immune signaling in bacteria(???????????)”??????????????????????(????)???,??“????????????????????”(Kongming),????????????????????“?????????????????????????????????????”??????,??????????

??,?????????????????????,?????????????“??????”????????????????1950??(??cAMP?cGMP)?,?????????????????,???????????????????????????,????????????????????,???????????,?????????KomA(??????????????????A)?KomB(??B)?KomC(????????????C)????????????????????????,??????????(DNK)??“???????”:KomA??????????DNK?????????????????????,????(dAMP)????dITP??KomC??NAD⁺,????“??????”??????,??????,??????“??????”?,?????????????????“?????????”??????????????????,???

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