??1????14????????????????? (??????????????? ??)“????,??,????”???14???????????,“?????????(ADC)?????,????????????????????????????,???????????????????????,??????????????????”

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????,??????????????????????????????,??,??????:??????????????????????????????????,??????????????,???????????????????????20%??30%??????,??:???????“????????????????????,?????”?????????????,???????????????,????????

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?????,??????-2(HER2)?,????“HER2?”?????????????“HER2????????????”???????????,?????????????????HER2??,?????????????????HER2?????????????,HER2??????????????

??????,????????????????,HER2?20%???,????????????,?????????????????????????????,ADC?????“HER2??HER2??,?????????????ADC????,?,?????????????????????????HER2?????????????,ADC??,??????????‘1+1>2’??????????????,???????”

HER2?????45%????????55%???????,?????HER2??????,????????????????HER2???,??HER2????????????????:“???????HER2??????????????,?????ADC???HER2??????HER2??????,???????????????????,????????HER2????????????????,????,??????????”

???????????????,ADC??,??,ADC????????????????????;????????

????,???????????2017??????,??????,????,?????????,?????????????????:“??????????????,????,??????????????”

??,??????,?,?,??,?????????????????????:???????????????,?,??????????40???????????????????B?????????,???????????????,?????????????????:????????????????????????????????40???????,???????????????,????(??????????) ????:???????????????

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