?? ?????|???????,“??”???????
????:1??????V:????
2?????95?????
3????????
4????????
5?????????
??,??????CAR-T(????????T????????????????)???????????“??????????????”?????
CAR-T??????????????,??:?????????????,?????????????????“????????????”?????????????????????“???,???????????”???????,??????????,????????????????????
??“????????”,???????????
????????????? 11 ???????,???????????????????,99.9??????????????????CAR-T???,????????CAR-T????????1?????????????????,??????????CAR-T??????????,??????????????,??120????CAR-T????????????60?????
8???????????,??,??????CAR-T?????????6???????????????CAR-T???????????????“??????”????????,??????,??????“??????????”???????????,????????“??????????????????????????”???????????????“???????????”?????,????????????????
?,?????:??“????????????????”???“???????????”????,??????????CAR-T?????“???????????????????”?????????????,????
?????,?“????”?????????????,?????????????????????,CAR-T????,???????????
???
??70%????60%?????????????????,?????????????“?”????????????41.3%?
???????????,???????,??????“????????????????????”????????????????????????,????????,?????“??”,??????????,?????????
???CAR-T??,“??”????????????????
????®(??)??????????,????2021????????????????,?????,??????,???????????
??????????????“??????”???????,??????????????????8????????????????,????????,??????????????/??,?????????????????,??????4?????CAR-T???????
??,??,???????29???????????,???????????30????????????????????????????,??99.9???????????/??~120???????????????/?????????????CAR-T????????????????,????
???????4???,??????????????,????????????????????????????????????????????,????????,???????,??????????????????CAR-T????,???CAR-T????????????????????????????
???????????????,CAR-T??????,????“????”,???????????“????”???????????????????????????,????????????????????CAR-T????????????????????????,????????
?,??????????,?????
?????«?»??,???????,???????“??”???????,???“????????????????”????????,????????????????????????????????????
??????????,CAR-T???????,???????:
??????????,CAR-T???100????????????,???“?????”??2023????????1.9?????????????(19.4%)???????1.7???????????(25.3%),?????????????,???????????????????“??”????????????????????,????????????????????“?????30??”???,?????????????????“??????”?
?????????????????????,?????????,?????,????????????,???????????????????????CAR-T?????????,???,???,??????????????????????????????????????,??“?”????
????
????????,??CAR-T??,???“?????????????????????,???”????,?????????????????“???????????”???
??????????????????????????,????????????????????????????,???????CAR-T???,????????
??1???,??“????”,???,???60?????
?????????????2024???????,???????,?,??????,?????????,???
???????:“?????????,?????????????,????”
????????,?????????,??????????,??????????“???????????”,???,??????????????????????,????????,???????????,??????????????????????,??,???
????????????,??????????????????“1+3+N”??????,??“N”??????,????????????????????????,?“N”????????,?????????
????????,?????????????????????
???????“?”?????????,???????????????,???????????????
????,??????,??????????,?,??????????
“????,??300????????????,??????????????????????????CAR-T????????????,CAR-T??????????????????,??,?????,?????‘??’?,????,????????,??????????????,???,??,?;?????,??????????????????,???????,????????‘??????’?”??????
?????“??”??,????????????????,?????????????
?????,??????????,??????????????????????????????,????,??????????????????????,??????????????50????????????????,????????????????,?????,????????????????????????????
??????????????,??????,??,??????????????????????????????????,??
?????,??,????????????????????????,?????????????“???????”,?,???????????????????????????????????,???
??????????,?????????????????????,?????,??????????
????????“???????????????”,??,?????????????????????????????????????
???100??????CAR-T???????,?,????,??????????????,????????CAR-T????26???????????????,??,????????4??,????????
???“???????????”,????,??,?????????????????????????????
“???????100?????????,???????????????CAR-T???,?????????????????????????,?????,?????????????????????????????????,??????????”????,???????????????,??????????????;????????????????????????;??,?????????????,?????????
CAR-T??
??????????CAR-T?????????????????????,?????????????????????????:CAR-T????????????????????CAR-T????????
?????????????????????????????????????CAR-T?????????????,??????,????,?????????????CAR-T??,????????????????,????????
??????????,???????????????“???????????????”????????,??????????????????,????????,??“????”?????????????????,?????????????????????,??????CAR-T????????????????,????????,????????????????????????
???????,CAR-T??,????DRG/DIP?????????,???????????“??????????”?????????????,??????????“???????????,?????????????????????,??????????”?????
??????????,“???????”?????????,???“???????”???????????????????,????CAR-T???
“??????????????????CAR-T??50%~70%????????????”??CAR-T???
???????,???????????CAR-T????,????????????????????????????????????????,????????,???????????CAR-T????????????????????????4.3???????????????,???????????????CAR-T??????????????????
??????,?,CAR-T?,???????,?????CAR-T??????
?????????CAR-T?????,?????????????????PD-1???,CAR-T??,???????????,??????????,?????????,????????????,?,???
???2024??3??1????????????CAR-T???????????????????????????(??????????????????)????????????,?????? CAR-T????????????????????11 ?????????,????????????????6???
?“2025-2030?????(CGT)??????????”??????????,???????????????,????????????????CAR-T???????????????,2023????????20%,???????184???????,?168?????????????????
???????,?????,?CAR-T????????????“??”?????????????????????????
?????????,2032?CAR-T???885.2??????????????????????????,???????????“??,?????????”(????????? ??????????????:??) ??????:???????????