????:1???????:????????????

2?????????

3?????????????

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???2??????????????20???(?????????)???,«???????-?»????,?????????????(?????:Ozempic)?????????(????:Mounjaro)??2?????19?????,?????????????????????????,????????????

???????,2023???,??2%???(semaglutide),?????-1??????????(GLP-1RA),????????????????????2???,??????????9???????????????????Ozempic????????Mounjaro??

2???19????????????????,???????????,????????????????????????????(NAION)??????????????,NAION????????(???????????????????????????????????????????????)?????????

????,??????GLP-1?,????????,????????????????NAION?????,?NAION????,???GLP-1RA???

?????,???,???????????????????????????«??????????????????????????????-??????????????????????????????»?????????,?????????9????????????????,????????,???????????????????

??,“?????????????????,??,??????????????,???????????????????????????,??”?

????????“GLP-1?”????????????????????????,??????????GLP-1?????????????2017????,?????,????????????????????,??????????

???????????????2024??,???2018.49????????,???290????????????????????????????,??“?????”K??????????,??????????Ozempic??2024????1203.42???????,??????????????26%;????????????????Rybelsus??233.01?????????????,?????????26%;??Wegovy?????????????582.06?,??81?,????????86%?

????2024?????,???Mounjaro?????,?????115.401?????????????????????????????????,?????Mounjaro????????Zepbound??????????????164.458?????

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2023????4????????????,?(???)??,????????????????,??????????????????????????????????????????????????????????????????????????????????????????????????????????????????(????) ???????????:????????????????