????:1????????:???????????

2??????????

3????????????

4???????

5????????

???,????????CAR-T(????T????)????????“????????”???

CAR-T??,??????:???????????,????“???????????”???“????????,????”??,????????????,????????

??“?????????”,??????????

??? 11 ??????????,?????????????,99.9???????CAR-T????????????????,????????CAR-T????1??,??????????CAR-T???????????????,???????????,?????????120??CAR-T???60?????????????

8?????????????,????,?????????????CAR-T?????????6?????????????CAR-T?????????????????????“?????????????”??????????????,??????????,????“??????????????????????????”???,??“?????”???????????“????????????”????,????????????

?????????????,?????:???????“???????????????????????????”????????????????????“???”???,????????????CAR-T???“??”?,?????

???,?????????“?????????????????”?????????,??????????,CAR-T???????????,??????

??????????

??????70%????????????????60%????????????,??????“????”??????????41.3%?

????,??,?????????????????“?”??????????????????,?????????????????,?????????????????????“???????????”,??,?????????

?????????????????????CAR-T??????,“??????????????”???

?????®(?????)????????,????????2021?,????????,???????,???

???“??????”?????????,??????8?????,???????????,???????????/??,????????????????,??4?????????????CAR-T???????????

??????????????????,???????????????,??29?????????????,??????????30???????????,????????99.9???????????/?~120????/?????????????????CAR-T???????,???

????????????????4?????,????,??????????????????????????,?????????????????????,?????,??????CAR-T???????????????,??????CAR-T??

????????,CAR-T??????????,?????“????????????????”,??????????“?”????????????,?????CAR-T?????????????????????????????,????????????????????

????????,??,????????????

???????«?????????????»??????????,??,?????“?????”??,?“???????????”??????????????,??????????????????????????????

??????????????????,CAR-T?????,??:

?,CAR-T?????100????,????“????????????”??????????2023???????????????????1.9???(19.4%)??????1.7?????(25.3%),????,????“???????????”????????????,???????????????????????“???????30??????”???????????,??????????????????“?????????????????”?

?????,???????????????????,???????,??,????CAR-T?????????????,??????,?????????????,???????????????????,????????“?????”????

???

???,???CAR-T?????????,????????“???,?????????”?????????,?????????“????????????????????????”????

???????????,?????????????????????????????????????????,??????????CAR-T????????????,????????

????????????????????????1???????????,???????????????“????????????????????”,??,????????60????????????????

??2024??,???,??????????,??????????????,??,??

?:“?????,???,???”

??,??????????????,???????????????????????????,???????“?????????????????????”,??????????????,??????,????????????,?????????????????????,???????????,?????????????????,????????????????

?????,??????????“1+3+N”??????????????,?????????“N”?????????,??????,???????????????“N”????????????,???

????,?????

??????????“????????”?????????????????????????,??????????????????,?????????

??,???????,?????????????,????????????????????,?????????????????

“?????????????????,???????????300???????????,????????CAR-T??????????,CAR-T?????????????????????????,???????,??,?????????‘??’????????,???,???????,?????????????????,??????,??????????????,??;???????,??????,????????,?????????‘????’?”???????????????????

??????????“????”??,???????????????????,????????????????????????

??????????????????????????,???,??????????????,??,??????,????????50?????,????,???,??????????????????????????????????

??????????????????????,??,???????????,???????????????????????????,???????????????

??,??,????????????????????????????????????????????,???????“???????”,??,??????????????????????,???

??,????,??,???

?????“?????????????????”,?????????,?????????????????

??????????????100??????CAR-T???????,??????????,????????????????,????????????????,????CAR-T????????????????????26?????????????,?????,?4???????,?????

??????“????????????????????”,????,?????????,????

“??????????100??,????CAR-T????????????????,????????,???????,???????,??????”??????????????,????????,??????;??????????;????????,????,????????

CAR-T????????????????

????????????????????CAR-T?????,?????????:CAR-T??????????????????????????????????????CAR-T???

?CAR-T????????????,???????????,?????,???????????CAR-T??????,????????????????????????,???????????????????

???????,????????“??”??,?,???????,????????“?????????????????????”????????????????,??????????????????,??????????????????CAR-T??,??????????????????,???

????????????,CAR-T????????,?????????????????DRG/DIP???????,??????????“?????”??,???????“????????,???????,???????????”???

???????,“???????????”???????,????????“???”???????????????????,????????????CAR-T??

“???????????CAR-T????????????????????????????50%~70%???”??????????CAR-T?????????????????????

?????????,?????????????????????CAR-T??????????????,??????????????????????????????????????????,?????????????????????,???????CAR-T?????4.3?????,??????????????????????CAR-T???????????

??,???????????,CAR-T????,??,???????CAR-T?????????????

???????????????????CAR-T???????,???????????????PD-1???,CAR-T???????,???,?????????,????????,??????????,????????????,???????????????????

?????????2024???3?1??CAR-T????????????????(???????)??????????,????? CAR-T?11 ??????,????6???????

??“2025-2030?????????????(CGT)?????????????????????????????????????”??????,??????????,??????CAR-T??????????????????????????,2023???????????20%,????????????????184???????????,?????168?????????????????????????????

????,?????,?CAR-T????“??”???????????

??,2032???CAR-T?????????????????????????885.2???????????????????????????????????????????,?????????????“????????,??????????????”(?????????? ???????????????:???) ??????:?????????????????