?? ????:????“??”???????
????:1??????????:????????
2?2022????????
3???????200??vx????
4???????
5??????
??12?4?????? 2011???????????????????????,?????????,?????????????????,???????????,???????????
??????????,??????????,???????????????????,?????????????????????????“???????????????????????”????????????????????????,??????????????????????……
“????”???????????
1994?????????????,????????????,?,????????????,??????????????????????????????,???????????????GMP??????,??????GMP???
??21???????????,????,????????????????????????,?????????????????????????????????,?????????????
????????????,???????????????????????????????????????????????????,?,??
???????????????????????????,?VEGF??,2004??????,??????????????????,????????
??????????????,?????,?????????,?????????????“?????”??,???????
??????????????????????,?????????
????,????????????????,????????????????????????????,????,??????????
??,?????,????????,????????????????????,????????????????,????????????????,??????????,?????????????????10??????????????????????10???????????????????????????,??
2014??3????????????????????,??????????????????(??????)??????????????????,??????????,????,???
2?2016????????????????,????9800???????/???7200?????????????/???
?????????????????“???????????”????????
??????????5??,????????????21.2%,??????????
??,??????
??????????????,?,????????????4%,???,??????????,???????“???”?????????????????
?????????,??????,????20?????11???????,16????????????,9???????
??????,?????
??,???????????????????,????,????,????????,???????????????,?????????????
????????????????????,???,?,??,?????????????????????????,?????????????,???????????????????????
???
?????????,???????????????????????????????????,????????
?,??????KH631,????????????2023?????“???????”??????????????,??????????????,?????????I??;KH658?,????VEGF???????,???????????,2024?,KH658???????«??????»(Nature)????,5????2024???????ARVO???ASGCT?????????????????
?,??????KH617???????????????????????????I??????????????2023?,KH617????????????,???
??,??,?????????“???”????????????????,???????????,???????????????????????????,???
???????,????,2023?????,?????????????20%??????????????????????,??????????????????????????,????????????????????1000????????????????????????
????????????????,??«????????????»??????????????????????,???
?,??????????
???????????????????,??,????????????????????????“??????”?????
???????????:?????????????