??|???????,“???????”?????

????:?????????:????

??,????????????CAR-T(??T??)???????“??????”??????

CAR-T???????,??:????????????,?????????“?”???????????“?????,??”???????,??????????????????????????????,??????????????

??“???????”,?????????

?????????? 11 ???????,??????????,99.9??CAR-T????????,????????CAR-T?????????????????1??????????????????,???????????CAR-T???????,???????,?????????????120?????????????????CAR-T?????????60??????

8???,??????????,??????CAR-T????????6?????????????CAR-T??“?”?????????????????,????????,?????????????“???????”??,???????“????????????????????”???????????????????“??????????”???????,????????????

??????,?:??????????“?”??????????????????“??????”?,????????????CAR-T??????????????“????????”???????????,?????????

??,???“??????????”????????????,????????????????,CAR-T??,????????????

???

?70%????????60%??????????????,?????“???”??????????41.3%?

???????,????????????,??????????“???????”?????????????????,???,????????????????“??????”,?????,?????

??CAR-T???????,“??”?????

?????????®(???)??,????2021?????????,??????????,??????????????????,????????

???????“??????????”?????????,???????????????8???,???,????????????????????/????,??????????????????????????????????,????????4?CAR-T????

??????????,???????????????????????????,????????29??,?30??????????????????????,??99.9?????/??~120????????/??CAR-T???,??????????????

??4??,????????,????????,???????????????,?????????????????????,??????????????CAR-T?,??????????CAR-T???

?????????????????????,CAR-T?????????????????????,????“????”,??“????????????”???,?????CAR-T???????????????????,??????????????????

???,??????????,?????

??????????«??»?????????????,?????,??????????????“????????????”??????????,?????????????“???????”?????????????????,???????????????????????????

?????,CAR-T????????????????,????????????????:

??,CAR-T?????????????100???????,???????????“?????”?????????2023????????1.9??(19.4%)?1.7???(25.3%),????????????,??????“?????????”???????,?“??????????????30?????????”???????????,????????????????????“??????????????????”?

?????????????,?,???????????,??????????,??????????????CAR-T??,????,??????,??????????,??“???????????????”????????

??????????????

?????????,???????????CAR-T????????????????,????????????????“???????????????????????????,?????”?????,???????????????“?”?????

????????????????,???????????????????????????????????????????,???????????CAR-T???,???????????????????

??1????,??“?”,?????????,?????????????????????60????

????????2024???????,??????????,??????????????????????????,?????????,??,????????

????????:“???????,??????,????”

??,??,???????,??????“?”,????,???,????,?????????,???????????????,?????,????????????????

??????????????,???????“1+3+N”?????????????????????????,?????????“N”??,????????????????????????????????,???????“N”???????????????????????,???????????????????????????

????????????,??????????????????????

???“?”???????????????????????????,???????????,????????????

???????????????????????????,??,?????,????,???

“?????????,????????300??????,??????????CAR-T???????????????????,CAR-T???????????????????????????????????,???????????,??????????????????,??????‘????????????????’???????,??????????,???????????,??????,?????,??????????????,??;?????????????????????,????????,???????,???????????????‘??’?”????????????????

??????????“????????????????????????”????????????????????????,????????????,?????????????

???????????,????????,???????????????????????,????????,??????????????????,??50?????,?????????,??????????????,???????

??,???????,???,?????????????????????????,????????????

??????????,??????????????????????????,???????????,???“??”,???????????????,??????????????,????????????????????

????????????????,????????????????????????????,????????,????

?????“?????????”,???,???????

???100??CAR-T??????,????????,???,?????????????????????????,??CAR-T???????????26?????,???,?????????????????4??????????,????

??“???”,??,??,????

“????100???????,????????????????CAR-T???????????,????,??????????????????????????????????????????????????????,???????????,??????????”????????????????????,??????????????????,?????????????????????????;???????????;?,?????????,?????????????

CAR-T????

?????????????CAR-T??,????:CAR-T????????????????????CAR-T???

???CAR-T??????????????????????????????,??????????????????,????,???CAR-T????,???????????????????????????????,?????????

????????,????“??”?,????,??????????????,??“??????????”???????????????????,??????????????????,???????????????????????CAR-T???????????,?????????,?????????

?????,CAR-T????????????????,?????DRG/DIP?????,??“????????”?????,????“?,??????,?????”??????

????????,“?????”????,??????“????????”?????????????????????????,???????????????CAR-T??????????????????????

“?????????????????CAR-T???????50%~70%?????????????????????????”????????????????CAR-T????????

?????????????????,????????????????????CAR-T????,????????????????????????,??,??CAR-T?????????????4.3???????????,????????????????????????CAR-T?????????????????

???,??,CAR-T????????,????????????,?CAR-T????????

?????CAR-T?????????????????,??????PD-1?????????,CAR-T???????,???,??????????????????????,????,??????,??,???

???????????2024??3?????????????????1??CAR-T????????????(????)???????????,???????????? CAR-T??????????11 ????????????,?????????????6?????

??????“2025-2030??????(CGT)?”??,?????,???????CAR-T??????????????????????????,2023??????20%,??184?????????????????????,?????????????????????168??????????????????????

???????????????,?????????????????????????????????????,??CAR-T??“??????????????”????????????????????

??????,2032????CAR-T??????885.2?????????????????????????????,??“????,????????”(??????????? ???????:????) ???????????????:????????