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?2025???2????21??????,?«??????????»??“Base-modified nucleotides mediate immune signaling in bacteria(???????????????????????)”????(??????)????????????????????,??“?????????????????????”(Kongming),???????????“??????”?????????????????,??????????????????

??,????????,????“???????????”??????????????????1950??????????????????(?????????????????????????????????????cAMP?cGMP)??,??????????????,??????,?????????????????,????????????,???????KomA(??????????????????A)?KomB(??????B)?KomC(??????C)???????,?????(DNK)?????????“??????????”:KomA???DNK???,????(dAMP)??????dITP????????????????KomC????NAD⁺,????????????????????????????“??????”?????????????????????,??,??“???”???????????,??“?????”???,??????????????

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