??????????????????????

????:????????????:??????????

?????????????????????????????????7???3?? (??????????? ???????????)?????????????????3???,?????

??????????????????(?????????????????????????????)??????????????????????????????????????HBV????????????????????????????????(siHBV),??,???

????????Signal Transduction and Targeted Therapy?

??????????,?????????????(HBV)?????(CHB)???????,??????????(RNAi)??(HBsAg)???

???,??(tLNP)??,??????????,??????????????????,????????????????RNAi????????HBV???,??????,???????HBV?T???????????,?????????????????(??????) ???:???