????:1????????:???????

2??????

3?????????

4???????

5????????????

?????????????????????2???????????20?????????????(????????)?????,«??????????-???»????,???(???????????:Ozempic)??(???:Mounjaro)??????2???19?,???????????????????????,???

????????,2023??,???????????????2%????????(semaglutide),??-1???(GLP-1RA),???2???,????9???????Ozempic?????????Mounjaro??????????

2?????????19????????????????,??,?????????????(NAION)???????????????????,NAION??????????????(????????????????????????)???

??????,???????GLP-1???????????????????????,????????????????????,????????NAION??????????????,????NAION?,??GLP-1RA???????????????

???,????????,?????«???-????»?????????????????,????????????????????????????9????????????????,?,??????????????

????,“?????????????????????????????????????,???????,?,?????????????,??”?

???????????“GLP-1?”??????????,???????????GLP-1????????????????2017?????,???????????,???????????????????????????????????????,???????????????

?????????2024????????,????2018.49???????????,??????????????????290???,?????“??????????????????????????????”K???????????????????,????Ozempic????2024?????1203.42??,??26%;???Rybelsus????????233.01???????????????????????????,?26%;??????Wegovy????????????582.06?????,?81????????????????,???86%?

?????2024?,????????????????????????????????????????Mounjaro??,?115.401??,??????????Mounjaro?????Zepbound?????????164.458????

?????????????????????????????????,GLP-1?????

2023????4??????????,?????????????????????(?????????)???,??????,?????????????????????????????????????????????????????????????????????????????????????(?????) ?????????:?????????????????????