????????????????,??CAR-T(??T????????)????“???????”???

CAR-T???????,?????:??,????????“??”?????????????????“??????????????????,??????????”??????,???????,?????????????

???“????????????”,??????

??????? 11 ??????????????????,????,99.9????????????CAR-T?????????????,???????????CAR-T???????????????????????????????????????1???????,?CAR-T??????????,???,???????120????????????CAR-T?60??????????????????????????

8???,????????????????,??CAR-T????????????6??????????????????????????????CAR-T????“??????????”???,?????,?????????????????“??????????????????????”???????????,????“???????????”???????????????????“????”????,???

?????????????????????,??:??????????????“????????”?????“??????????”???????,????????????????????????CAR-T??“???????????”???????????????,???????????

??????????????????,?????“??”?????????????,?????????????????????????????????????,CAR-T??????????,???

????????????

???????70%????????60%??????,???????“???????????????”??41.3%?

??,???,???????????“???????????????????????????”???????????????????????????????????????????,???,??????????“????????”,????????,?????????

???CAR-T?,“?”?????????????

??????????®(???????????)?????????????,????2021???????,?????,?????????????????,????

??????????“??????????????”?????,??????????????????8??????????,????????,????/????????????????????????,???????????????????????????????????????????????,??4??????????CAR-T???????????????????????

??,???,???29?,???????????????30???????????????????,????????????99.9?????????/??~120????????/?CAR-T???????,???

??????4?????????????????,????,??????????????????????,?????,?????????,?????????????CAR-T????????????????????,????????????????????????CAR-T????????????????

?,CAR-T????,??“????????”,?????“??????????”?????????,????????CAR-T??????????,??

????????????????,?????????,????

??????????????«??????????»??,???????????????????,?????????????????“??????????”????,????????“??????”??????????????????,??????????????????????????????

???????????,CAR-T??,??:

??????????,CAR-T?????????100???????????,???????“???”??????2023???1.9???(19.4%)???????????1.7??(25.3%),????????,????????????????????“???????????”?????????????,???????“????30??????????????”???,??“?????????”?

????????,???????????,??,?????????,?????CAR-T?????,?????????????,??,??????????,???“????”?????????????

????????????????

?????????????,???????CAR-T??,??“????????????,????????????”???,????????????????“????????????????????”??????

???,????????????????????????????????????????????????????????,??????????CAR-T????????????????????,????????

?1???????????,????????“????”,?????????????,???????60????????????????

??????????????2024??,???????,??????????,??????????????????????????,??,???

?????????????:“????????????????,?????????????????,???????”

???????,??????,??????,????????“??”,??????????,????????????????????,??,???????????????,????,???????????,????????????

??????????????????,??“1+3+N”??????????,???“N”??????,????????????????,????“N”????,???????????????????????????

?????,?????

??“??”?????????,??????????,????

????????,??,??,???????,?????

“?????????????????,???????????????300???????????,???????CAR-T??????,CAR-T????????????????????,??????????,????????????????,?????‘?’??????????????,??,???????,??,????????????????,??,?????;?????????????,?????????????????,???????????,??????‘???????????????????????’?”????

?“?”??,?????????????????????????,??????????????????????

???????????,?????,????????????,??????????????,????????????????????????????,??50???????,??,???????????,??????????????

?,???????????????????????????,????,??????????????????????????????????,????????

??,??????????????,??????,?“?????????????”,???,?????????????????????????????????????????????,????????????????????

???,??????????????,??????,?????????

??“???????”,??????,?????????

??????100?CAR-T?,????????,??,????????,?????CAR-T????????????????26?????,??,?4???????????,???????

??????“??????”,????????,???,????????????????

“????????????100????????????????????????????,??????????????CAR-T???,??????????,?????????????????????????,?????????????????????????????????????????,???????????????”??????????,??????????,?????????????????????;??????????????;??,????,???

CAR-T???

?????????????????????CAR-T??????????,??:CAR-T?????????????????????CAR-T?????????

???????????????????????????CAR-T???????????,??,???????,??????????????CAR-T???????????,?????????????????????,????????

?,????????“???????????”????,???????????????,?????,??“?????”??????????????????????????,??????,?????????????CAR-T???????,?????????,????????????????

????????????????,CAR-T??,????????????????DRG/DIP?????????????????????,?????“???”???????????????????????????,????????“??????,???????????,????”?????????

??,“?????”??????????????,????“???????”????????????,???CAR-T???

“?????????CAR-T?????50%~70%??????????????????????”?????????CAR-T?????????????

???,??????????????????CAR-T?????????,???????????????????????????????????????????????????????,???,?????????????CAR-T????????????4.3??,?????????????CAR-T???????

??????????????,?????????????????,CAR-T????????????????,?????????????????????????,????????CAR-T???????????

???????CAR-T????????,??????PD-1???????,CAR-T???????????,???????????,?????????,?,?,?????,?????

????????2024???????3?1?CAR-T??(???)????????,??????????????? CAR-T???????????11 ???????,??????????6????????

???????“2025-2030?????(CGT)????”???,?,??CAR-T?????????,2023??????????20%,?????????184??,???168?????????????

??????????,??,??????CAR-T??“???????????????”??

???,2032??????CAR-T???????????????????885.2??????????????,????“??????,??????????????????????”(??????????????? ??????????:??????????????????????????) ?????????:??? ??“??????????”

?? ???????|???????,“??”?????

????:1???????????:??????

2???????????

3????????

4???????

5???????????

????????????????,??CAR-T(??T????????)????“???????”???

CAR-T???????,?????:??,????????“??”?????????????????“??????????????????,??????????”??????,???????,?????????????

???“????????????”,??????

??????? 11 ??????????????????,????,99.9????????????CAR-T?????????????,???????????CAR-T???????????????????????????????????????1???????,?CAR-T??????????,???,???????120????????????CAR-T?60??????????????????????????

8???,????????????????,??CAR-T????????????6??????????????????????????????CAR-T????“??????????”???,?????,?????????????????“??????????????????????”???????????,????“???????????”???????????????????“????”????,???

?????????????????????,??:??????????????“????????”?????“??????????”???????,????????????????????????CAR-T??“???????????”???????????????,???????????

??????????????????,?????“??”?????????????,?????????????????????????????????????,CAR-T??????????,???

????????????

???????70%????????60%??????,???????“???????????????”??41.3%?

??,???,???????????“???????????????????????????”???????????????????????????????????????????,???,??????????“????????”,????????,?????????

???CAR-T?,“?”?????????????

??????????®(???????????)?????????????,????2021???????,?????,?????????????????,????

??????????“??????????????”?????,??????????????????8??????????,????????,????/????????????????????????,???????????????????????????????????????????????,??4??????????CAR-T???????????????????????

??,???,???29?,???????????????30???????????????????,????????????99.9?????????/??~120????????/?CAR-T???????,???

??????4?????????????????,????,??????????????????????,?????,?????????,?????????????CAR-T????????????????????,????????????????????????CAR-T????????????????

?,CAR-T????,??“????????”,?????“??????????”?????????,????????CAR-T??????????,??

????????????????,?????????,????

??????????????«??????????»??,???????????????????,?????????????????“??????????”????,????????“??????”??????????????????,??????????????????????????????

???????????,CAR-T??,??:

??????????,CAR-T?????????100???????????,???????“???”??????2023???1.9???(19.4%)???????????1.7??(25.3%),????????,????????????????????“???????????”?????????????,???????“????30??????????????”???,??“?????????”?

????????,???????????,??,?????????,?????CAR-T?????,?????????????,??,??????????,???“????”?????????????

????????????????

?????????????,???????CAR-T??,??“????????????,????????????”???,????????????????“????????????????????”??????

???,????????????????????????????????????????????????????????,??????????CAR-T????????????????????,????????

?1???????????,????????“????”,?????????????,???????60????????????????

??????????????2024??,???????,??????????,??????????????????????????,??,???

?????????????:“????????????????,?????????????????,???????”

???????,??????,??????,????????“??”,??????????,????????????????????,??,???????????????,????,???????????,????????????

??????????????????,??“1+3+N”??????????,???“N”??????,????????????????,????“N”????,???????????????????????????

?????,?????

??“??”?????????,??????????,????

????????,??,??,???????,?????

“?????????????????,???????????????300???????????,???????CAR-T??????,CAR-T????????????????????,??????????,????????????????,?????‘?’??????????????,??,???????,??,????????????????,??,?????;?????????????,?????????????????,???????????,??????‘???????????????????????’?”????

?“?”??,?????????????????????????,??????????????????????

???????????,?????,????????????,??????????????,????????????????????????????,??50???????,??,???????????,??????????????

?,???????????????????????????,????,??????????????????????????????????,????????

??,??????????????,??????,?“?????????????”,???,?????????????????????????????????????????????,????????????????????

???,??????????????,??????,?????????

??“???????”,??????,?????????

??????100?CAR-T?,????????,??,????????,?????CAR-T????????????????26?????,??,?4???????????,???????

??????“??????”,????????,???,????????????????

“????????????100????????????????????????????,??????????????CAR-T???,??????????,?????????????????????????,?????????????????????????????????????????,???????????????”??????????,??????????,?????????????????????;??????????????;??,????,???

CAR-T???

?????????????????????CAR-T??????????,??:CAR-T?????????????????????CAR-T?????????

???????????????????????????CAR-T???????????,??,???????,??????????????CAR-T???????????,?????????????????????,????????

?,????????“???????????”????,???????????????,?????,??“?????”??????????????????????????,??????,?????????????CAR-T???????,?????????,????????????????

????????????????,CAR-T??,????????????????DRG/DIP?????????????????????,?????“???”???????????????????????????,????????“??????,???????????,????”?????????

??,“?????”??????????????,????“???????”????????????,???CAR-T???

“?????????CAR-T?????50%~70%??????????????????????”?????????CAR-T?????????????

???,??????????????????CAR-T?????????,???????????????????????????????????????????????????????,???,?????????????CAR-T????????????4.3??,?????????????CAR-T???????

??????????????,?????????????????,CAR-T????????????????,?????????????????????????,????????CAR-T???????????

???????CAR-T????????,??????PD-1???????,CAR-T???????????,???????????,?????????,?,?,?????,?????

????????2024???????3?1?CAR-T??(???)????????,??????????????? CAR-T???????????11 ???????,??????????6????????

???????“2025-2030?????(CGT)????”???,?,??CAR-T?????????,2023??????????20%,?????????184??,???168?????????????

??????????,??,??????CAR-T??“???????????????”??

???,2032??????CAR-T???????????????????885.2??????????????,????“??????,??????????????????????”(??????????????? ??????????:??????????????????????????) ?????????:???