????:1???????:????v

2???????

3??????????

4?????v

5?????????????

??????????????,??CAR-T(????????T????????)??????“????????”??

CAR-T???????,?:??,?????“?????????????????”?????“???,?????????”???????????,??????????????????,????????????????????????????

??????“???????”,??????

??? 11 ??????????????,?,99.9??CAR-T????????????,???????????CAR-T???????????1?????????????,????????CAR-T?????,????????,????120??????????????CAR-T????????????????????????60?????

8?????????????,?????????????????,?????????????CAR-T???????????????6?????????????????????????????CAR-T??“?????????????”??,???????,???“???????????”??????,??“????????”??????????????“???”????,????????????

???????????,??:??“???”???????????????“?????”?????????????????,?????????????????????????????????????CAR-T??????????“??????????????”??,??????

??,?????????“???”?????????,????????????????????,CAR-T?????,???????????

??

????????????70%????????60%?,???????????“??????????????????????????”??41.3%?

???????,?????,??????“??????????”?????????????????????,????????,?????????????????“????”,??,???????????

?????CAR-T???????????????????,“???”???????????

??????????®(????????)???????????????,???????2021???????????,??????????????????????????,???????,????????

???????“?”?????,??????????8???,???????,??????/??????????,??????????,???????????4??CAR-T???????

???????????????,??,????????29???????,???30?????????????,???99.9?????/?~120????????/??????????????????CAR-T??,??????????????????????

????4??,??????,??????????????????????????,??,???????????????,??????????CAR-T??????????????,?????????CAR-T?????????????????

?????,CAR-T????????????,?????“????”,????????????????????“??????????”???,????CAR-T??????????????????????????,????

???????????????????,????,???????????

???????????«?????????????????????»?????????????????????,??,???“??????????????”??????????,?“??”???????,???????????????????????????

???????????,CAR-T?????????,???:

??,CAR-T?????????????????100????,????????????????“?”?????????2023????1.9??????????????????(19.4%)???????1.7??????????????(25.3%),?????,???????????????“??”???????????????????,??????????????????“????????????????????30???”??????,????????????????????????“????????”?

????????????????,?,????????,????,???????????????CAR-T????????,??????,??????,??????????????????,??????“????????????????????????”?????????????

???????

???,?????????????CAR-T??????????,??????????“??,??????????”??????,?“???”??????????

?????,?????????????????????????????????????????????????,???????????????CAR-T?,???

?????1????????????????????????,????????????????????“????????”,?????????????????,????????????????60???????

??????????????????2024??????,??????,??????????????????????,????????????????????????????????????,?????????,?????

??:“???????????????,???????????,???”

?????????????,?,??,????“?”,????????,?????????????,???????????,???,???????????,??,????????

???????????,?“1+3+N”????????????????,??????“N”?????????????????????,?????????????,??????????????????“N”??,??????????????

??????,????????????

??“?????????????”?????????????????????,????????????????????????,?????????????

???????????,???????,????????????,???,?????????????

“?????????,??????????300???,???CAR-T??????????,CAR-T?????????????????????????,??,???,?‘???????????????????????’????????,???????,??,??,?,???????,?????????;?,?????????????????????,???,????‘???????’?”????????

????“???????”???,??????????????????????????,?????????????

??,???????????????????,??????????,???????????????,?????????????????,??????????50??,???????,???,??????????????????

???????????,??,????,????????????????????????????????????,??????????

?????????,?????,??????????,???????“??????????????????????”,????,????????????????????????????????????????????????????????????????????,?????????????????????????????

????,?????????????????????????,???????????????????????????,????

??????????????“??????????????”,??,?????????????

????100????????CAR-T?????????,??????,???,?????????????????????????????,???????????????????????????CAR-T???????????26?????,?????,??????4??,????

????????“??????????????”,?????????????,????????,?????

“??100???????,?????????????????CAR-T??,??????????,???????????????????????,?????????????????????,???????”??,????????????,????????????;?????????;??,??????????????,???????????

CAR-T????????

??CAR-T??,??????:CAR-T????????????????CAR-T????????????????

???????CAR-T???,??????????,?????????????????????,???????CAR-T?????,??????????????????????????????,?????????????

?????????,?????“????????????????????”???????????,??,??????????????????????????,????“???????”??????????????????,???????????????,??????????????CAR-T?????,???????????????,?????????

???,CAR-T???????,????DRG/DIP????????,??????????????????“?????”?????????,??????“????????????,??????????????????,???????????”?????

????????????,“???????”????????,??????????“??”??????????,??CAR-T??????

“?????????CAR-T???????50%~70%?????????????????”??CAR-T????????????

??????????,?CAR-T???????,??????????????????????????????,?????,????????CAR-T???????????????????4.3??,??????????CAR-T????????????????

???,????????????????????,CAR-T????,???,??????????????CAR-T?????

??CAR-T????,??????PD-1???????????????,CAR-T??,???,?,???????????????????????????,?????,??,?????????

?????????????????????2024???????????3?????????????????????????????????????1?????????CAR-T???(???)?????????????,????????? CAR-T?????????11 ???,????6???

???????“2025-2030????(CGT)??????”?,???????????????,?????CAR-T????,2023???????20%,??????????184??,??168?????????????????

???,??????????,?????CAR-T??????“??????????”????

??,2032??????????CAR-T??885.2?????????????????????????????,?????????“??,????????”(?? ??????????????????????????????:????) ?????????????:???