???????|???????,“??”?????

????:???????????:??????????

???????????,???????????CAR-T(????????????????T???)???????“??”???????????

CAR-T???????????,????????:???????????,????????????????????“????”?????????“????,???”?,??????????????,????????

???????“????”,???????????

???????? 11 ?????????,??????????,99.9?????CAR-T????????,??????????????????????????CAR-T????????????????????????????????????????1???????????,???????CAR-T??,??,??120?????????CAR-T?????????????60??????

8?????????????,??????????????????,????????CAR-T??6?????????????????????????CAR-T??????????????“??”????????????,????????????,??????“?”?,?“????”??????????????????????“???????”???????????,?????????????????????????

???????????,?????:?????“??????????”???????????“??????????????”????????????????????????,????????CAR-T????????“?????”??,???????????

??????????????,????“?”????????????????????????,?????????????????????,CAR-T??????,?????????

?

?????70%????????????60%????????,??????????“????????????”?????????????????????41.3%?

????????,??,???“????????????????????”??????,??,???“??????????”,??,????

?CAR-T???????,“???????????????”????????

???®(??)???,???????????2021??????,????,?????????????????,??

???????????????“?”???????????????,??8?????,????????,??/???,??????????,??????????4????????CAR-T???????

??????,?????????????????,???????????????????????29????????,?????????????????30???????????????????,???????????99.9????/????????????????~120??????/????????????CAR-T?????,??????

????????????????????????4??,?,??????????????,??,??????????????????????,???????????CAR-T??????????,????????CAR-T?????????????

??????????????,CAR-T?????????????????????,???????“??”,???“??”??,?????????????CAR-T??????????????????????????????,?????????????

??,?????????????????????,??????????????????????

????«??????????»??????????????????,??,??“??????”???,???“????????”????????????,??????????????????????????????????

???????,CAR-T????????????,??????????:

?????,CAR-T????????????100?,??????????“???????”????????????2023?????1.9?????(19.4%)??????????????1.7?????????(25.3%),??????????????????????????,??“?????”????????,??“???????????????????????????30??????”?????,???????????“????”?

???,??????????????????????????,??,???????????,?????????????????????CAR-T??????,???????,?????????????,????????????????,??“?????”??????????????

???????????????

????,?CAR-T???????????????,????????“???????????????????,????????”???????????,?????????“?????”?????????

???????,??????????????????????,??????????CAR-T????,???????

???????????????1????????,??????????“?????”,????????????????,???60?????

?2024????,??????????,??,????????????????????,????,??????????????????

??:“?????????,????,???????”

??,???????,???????,?????????“???????”,???????,???,????,?????????????????,?????????????,??,??????????

??????????,?????????“1+3+N”???????,????“N”???,?????????????,????????“N”???????????,????????????????

?,?????

?????????“?????????????????????”?????????,???????????????????????????,?????????????????

??????,??????,???????,??????????,???

“?????????????????,???300??????,????CAR-T??????????????,CAR-T??????????????????,???????,????????,???????‘??’????????,?????,???,????,?????????,??????????,???;????,?????,??????????,????????‘?’?”??????

?“?????????”???,????????????,?????????????????????????????

????????????????????,?????????????????????,?????????????????????????????,??,?????????????,???????????????50???????,????,???????????,????????????????????

?,??,??????????????????,?????????????????????????????????????????????????,???????????

????????????,??????????????????,???????????????????,??????????????????“????????????????????”,???,??????????????????????????????????????????,?????????

??,????????????,????,??

?????“??????????????????”,????,?????????????

??????????100???????CAR-T??,???,???????????,??????,??????CAR-T??????????????????????????????26?????????????????????????????????????,??,??????????????4????????????????????,???????????

??????????????“???????”,????????????????,???????,??????

“???100??,????????CAR-T????,???????????,???????????????????????,??????????????????????????,?????????”???,?????????????,???????????????????;???????????????????????????????;???????????????????,??????????????????,??????

CAR-T??????????????

??CAR-T???????????????,??????????????:CAR-T?????????????????CAR-T????

?????????????CAR-T??????,??,???,?CAR-T?????????,?????????????,??????

???,?????????????????????????????????????“??”??????????,???????,??,???“?????????”??????,??????,???????????????????????????????CAR-T?????????,?????????????????,???????????

????,CAR-T????,????????????????????????????DRG/DIP???,??“??????”??????,?????????????????????“??,??????,????????????”??

??????,“???????????”??,?????“???????”?????????????????????????????????????????????????????,??????????????????CAR-T????????????????

“????????CAR-T????????????????50%~70%??”?????????????CAR-T?????????

????,?????????CAR-T???,???????????????????????????????,??????,???CAR-T?4.3???????????,???????????????CAR-T??????

?,??,CAR-T???????????,??????????????????????????,?????CAR-T???

?CAR-T?????,?????????????????????PD-1?????????,CAR-T???????,???????????,??,???????????????????????????,???,??,?????????????

??2024????????3?????????????1??CAR-T?????(??????????????)?????????,??????? CAR-T???11 ?????????,??????????????6????

???“2025-2030?????(CGT)??”???????,?,??CAR-T???????????????,2023?????????????20%,??????184??,????168????????????

????????????,???????,?????CAR-T?????“??????”???

?????????????????????????,2032??????????CAR-T???885.2??????????????????????,??“????????,????????????”(????????????????????????? ???????????:???????) ?????????????????:????????????????