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????2025?????2????21??????,??????«????????????????»???“Base-modified nucleotides mediate immune signaling in bacteria(??????????????????)”???????????????(?????????????)???,????“???????????”(Kongming),???????????“????”??,???????????????????

??,????????,????“??”????????1950?????????????????????(???????cAMP?cGMP)????,?????,?????????????????,????????????????,????,??KomA(???????????????????????A)?KomB(????B)?KomC(????????????C)????????????,?????(DNK)??????????“?????????????????????????????????????”:KomA???DNK????????????????????????????,?(dAMP)??????????dITP???KomC????????????????????NAD⁺,????????????“?????????”?????????????????????????,??????,??“???????”????,?“?”?????,??????????????

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