?? ???????|???????,“?????”??
????:1??????:??????
2????????
3??????????
4??????????
5?????????
?????,?CAR-T(?????????T??????????)??????“????”?????????
CAR-T??????????????,????:????????,????????“???????”??????“???????????,????”??,????????????,???
?????“??????”,???
??????????? 11 ???????,???????????????????????????,99.9??????????????CAR-T???????,?????CAR-T??????????????????1??????,????????????CAR-T???????????,?????,?????120?????????CAR-T??60????????
8??,??,????????????????????CAR-T??????????????????6?????CAR-T?????????????????“??”???,?????????????????????????????????????,?????????????????????“?????”???????,???“??????????”???????“???”????????,?????????????????????????????
????,??????????????????????????:????????????“??”?????????????“???”???,?CAR-T??????????“???????”???????????????,???????????????
?????????????,??“???”????????????????,???????????????,CAR-T???????????,?????
?
????????70%??????60%?????????????,??????????“??”??????????????????????41.3%?
??????,????????????,???????“??????????”???????????????,??,????????“????”,?????,???????????????
?????????????CAR-T???????,“???????”??????????
??????®(?????????)??,??2021?????????????????????,????,??????,????????
????????“???????????”??????????????????,???8?????,???????????,??????????/??????????,??????????????????????????????????,??4????????????????????CAR-T???????
???,?????????????????????,?????????29??,???30???????????????????????????,??????????99.9??/????????????????????????~120??/???????CAR-T??????????,?????????????????
??????????????4??,?????????,?????????????????????,?,???????????????,??CAR-T?????????????,????CAR-T????????
?????,CAR-T?????,?????????????????“???????????”,??????“???”??,????????????CAR-T????????,??????????????
????????????????,????,?????
???????????????«??»??????????,??,????????“?”??????????,??????????“??????????????????”????????????,???????????????????????
?,CAR-T???????????????,?????????????:
?????????????????????,CAR-T?100??????????????????????????,???????“???????”??2023??1.9??(19.4%)????1.7???(25.3%),??????????,?????????????????“?????”???????????????????????,?????“??30??”??,??????????“??????????????????????”?
?,???????,??,???????,????????????CAR-T???,??????,????????,????????????,????????????“????????????”???????????
????????????????????????
??????????????,????????CAR-T???????????,??????????“???????????????,????”?????,?????????“??”?????
???????,?????????????????????????????????????????????????????,??CAR-T?,?????????
???????????????1??????????,???????“???????????????????????????”,?????????,???60????????????????
?????????2024?????????????????,??,???,???,??,???
????????:“??????,????????,????????????”
????????,???,??????,????????“??”,??,?????,?,???,?,???,????
????,??????????“1+3+N”???????????????,??????“N”???????????,?????????????????????????,???????“N”??????????,????????????
????,???
??“????????”???????????????????,?????????????,???????
??????????,???????,???????????,??,?????????????????????????
“??????????????????,????????????300?????????,???????CAR-T??,CAR-T?????????????,????????????????,???,???‘????????????????????’???????????,?????,?????,??,????????,?????,???;???,???????????????????????????????,???????????,??????‘???????’?”?????
????????????????“???????????”???,???????????????????,?????????????????
??,???????????????,??????????????????????????????????????,???????????????????,?????????,???????????50????????,????????????,????,????????
?????,??,??,???????????????????????,????????????
?????????????????????,????,?????????????????,??????“???”,????????????????,???????????????????????????????????????????????????,??????????
??????????????,?????????,???,????
?????“??”,????????????????,??????????????
?????????????????????????100?????????CAR-T??,?????????????????????????,??????,????????????????????????????????,???????????CAR-T???????????26?????????????,?????????,???????4?????????????????,?????????
???????????????“???????????????”,??????????????,??????,????????????????
“???????100???,??CAR-T?????,?,??????????????????,????,???”????????????,????????????????????????????,??????????????;???????????;???????,??,????
CAR-T???????????
??CAR-T???,????????????????:CAR-T????????????CAR-T??
????????????????CAR-T?,??????,???,???????????????CAR-T??????????,???????????????,????????????
??????????,????????“?????????”??,??????,?,?????????????“??”????????????????????????,?????,???????????????????CAR-T?????????????????,????,?????????????????????
??,CAR-T?????????????,??????????DRG/DIP?????????,????????????“???????????”??,???????“?????,????????,???????????????????”??
??????????????,“??????????????”??,????????????????????“????????????????????”???????????????????????????????????????????,?CAR-T????
“??????????????????CAR-T?????50%~70%???????????????????”???????CAR-T?????
????????????,?CAR-T?????,?????????????????????????????,????,???CAR-T???4.3????????,??CAR-T?????
??????,???????????????,CAR-T?,??,???????CAR-T?????????
??????????CAR-T?????????????????????????????????????,?????PD-1???????????????????,CAR-T??????????,??????????????,????????,????????????,??,????,?????????
?????2024????????3???????1???????????CAR-T???(???????????)??????????????????,??? CAR-T???????????11 ?????????????,?????????????6??????????????????
??????????????“2025-2030?????????????(CGT)?????”?????????,???????,??CAR-T??????,2023??????????20%,????184??????????????????????????????,???????????????????????????168?????????????????????????????
???????,???,?????????CAR-T????????????????“???????????”???????????????????????????
?????????,2032???CAR-T????885.2??????????????????????,??????“?????????????,??????????”(???? ??:?) ???????:????????????????????????