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??2025??????????????????2????21??,????«??»??????????“Base-modified nucleotides mediate immune signaling in bacteria(?)”?????????????????????(?????????)?????????????????,?“??????”(Kongming),??“??????”???,???????

?????????????????????????????????????,???????,??????“???????”????1950???????(?cAMP?cGMP)??????????????????,?????????????????????????????????,????????????????,???????????????????,?????,??????????????????KomA(?????????????A)?KomB(???????????B)?KomC(??????????C)?????????????????,?????????????????????(DNK)????“?????????????”:KomA??DNK??,?????????(dAMP)??????dITP??????KomC????????????NAD⁺,????“??????”?????,??????,??“????”??,??????“????????????”???????,??

?,“?????????????”????????????????????,???????????????????????(????????????????????KomB-KomC????KomA)??????????????,????????????????dITP??:???????????,????(????????????????????????????ADA???????????)??,?????

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