???????????????????11??????10??(? ?????????)??????????????????????????????????????113????????;???????????14.1????;????:?;??FDA?;??????;??????????????KRAS G12C???;??????????;??????????????????????……????11??4????????????-11????10????????,?????????????????????????

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11??????5?????????????????????????????????????????,?,?,?????????????????????????????????“?????????????”??????????????????????????????????“????”???????,???????????????????????????,????????????????,??????????????????

??????:?????????????113?????????

11?7????,???????????????????????????,???40?????????????????????,??????????????????????????“???????”??????30??????,??,113???????????????«?(ICD-11)»?????,????????????????????????????????,??????????,?????????ISO/TC249,??113?????????

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11????7?????????,?App?????????,?,????????????,?2.1????????14.1?????????????,??????????571%??????????????????2022???4??????????,?,?????????(????????)???????,???????????????????(600436)????

??:???????????

11???8?,?,???????????????????????????HRS-2189?????HRS-5041 ?????????????????????????HRS-1358???????????????HRS-8080???????SHR-8068??????HRS-620 ?????«?????????????»,???????

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11??????????????8???,????????????????,????????????(FDA)??????????(New Drug Application,NDA),??????????,????????????????? FDA ?????????????????????????????????,??????????(EGFR)20 ???????(Exon20ins)?(NSCLC)?????????? FDA ????????????????

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11?6?,??????,?®(????????)?????????,???????????????????????(ANCA)????????(??[GPA]????[MPA])???

????KRAS G12C????????????

11???????????9??????????????????????????,??????????????????,?KRAS G12C?????????????????(????????????????“???????????????????????????”)????????????????,?KRAS G12C????????(NSCLC)????????,??????????????????,????????????1???????????????????,????????????????????????5??????????????????????,?6???????KRAS G12C??????????????????????,????????????KRAS G12C???????????????????????

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11??????5?????????????????????????????????????????,?,?,?????????????????????????????????“?????????????”??????????????????????????????????“????”???????,???????????????????????????,????????????????,??????????????????

??????:?????????????113?????????

11?7????,???????????????????????????,???40?????????????????????,??????????????????????????“???????”??????30??????,??,113???????????????«?(ICD-11)»?????,????????????????????????????????,??????????,?????????ISO/TC249,??113?????????

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11????7?????????,?App?????????,?,????????????,?2.1????????14.1?????????????,??????????571%??????????????????2022???4??????????,?,?????????(????????)???????,???????????????????(600436)????

??:???????????

11???8?,?,???????????????????????????HRS-2189?????HRS-5041 ?????????????????????????HRS-1358???????????????HRS-8080???????SHR-8068??????HRS-620 ?????«?????????????»,???????

???FDA???

11??????????????8???,????????????????,????????????(FDA)??????????(New Drug Application,NDA),??????????,????????????????? FDA ?????????????????????????????????,??????????(EGFR)20 ???????(Exon20ins)?(NSCLC)?????????? FDA ????????????????

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11?6?,??????,?®(????????)?????????,???????????????????????(ANCA)????????(??[GPA]????[MPA])???

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11???????????9??????????????????????????,??????????????????,?KRAS G12C?????????????????(????????????????“???????????????????????????”)????????????????,?KRAS G12C????????(NSCLC)????????,??????????????????,????????????1???????????????????,????????????????????????5??????????????????????,?6???????KRAS G12C??????????????????????,????????????KRAS G12C???????????????????????

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