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??2025???????????2??????21????,???«?»???????“Base-modified nucleotides mediate immune signaling in bacteria(????????????)”?????????????????(????)???????????,?“?”(Kongming),???????“??”??,??????????????????

??????,??????????????,??????????“????????????????????”?????1950?????????(???????????cAMP?cGMP)?????????????????????,???????????,???????????????????????????????????????????????,????,???,???KomA(??????????????????A)?KomB(???????????????B)?KomC(??C)????????????????,??????????(DNK)??????????????????“??????”:KomA???DNK??????,????????????(dAMP)??dITP?????KomC?NAD⁺,????????????????????“?????????????????”?????????????????????,????,?????????????“????”?????????????????,?“??????”?????,?????

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