????:1??????:????????????

2??????????????

3???????100?

4?????????

5??????????

???????????????????,???????????CAR-T(??????T???)??????????????????????????“????????????????????????”??

CAR-T????????,?????:?????????,?“??”?“??????,???????????????”??????,??????????????,???????????????????????????

?????????????????“??”,????????

?? 11 ?????????????????,???,99.9?????????????CAR-T??,????CAR-T???????????????????1????????????????,??CAR-T??,??,??????????????120???????????CAR-T?????????60?????????

8????,?????????????????????????,????????????????CAR-T?????6??????????????????????CAR-T????????“?”????????????????????????,???????????????,????????“????”??????????,??????????????“???????”??????????????“????????????”???,???

???????????????,??????????:????????????“???”????“??????????”???,????????????CAR-T?????????????“??????????”????,?????????

??,????“???”????????????????????,???????????????????,CAR-T????????????,????????????????

???????

???????????????????70%????????60%??????????,???“??????”?????41.3%?

???????????????????????????,??????,???????????????“???????”?????????????????,?????????,???????“????????”,?????????,??????????????

??????CAR-T?,“????????????”????

????®(????????????????????)????????,?2021???????,????????????,???????????????????????????,????

????????????“????????”??,???8??,??????,??????????????????/??????????????,??????????????????????,???????4??CAR-T????????

????,???,??29???????????????,?????30???????,???99.9?????????/??~120????/????CAR-T??,???

??4????????????????,???????????,??????????????????????,????,???????????????????,???????????????????CAR-T??,???????????????????CAR-T???

??????,CAR-T???????????,???????“?????????”,????????????“?????”????????,???????????CAR-T???????????????????,???

???????,????,??????

???????«?»?????????????,???????,???“??????????”?????????,??“??”??????????,???????????????????????????????????????????????????????????????????????????

??????????,CAR-T???????????,??????????:

??,CAR-T??100??????????????????,???????“???????????”?????????????????2023?1.9??????(19.4%)?????1.7??????(25.3%),????????????????????????,???“???????????????”????????????????????,?“???30?”???????,?????“????????”?

????????????????????,?????????????????,??????,????????????,??????CAR-T????????????????????,???????,???????????????????,???????????,???????????“?????”????????????

????????

?????????????,????CAR-T????,???????????“???????,??????????”??????????????,??“??????????????”??????????

????????????,???????????????????????????????????????????????????????????????????,??????CAR-T????????,????????????

???1??,??????????????“??”,??,??60???????

??????????????2024?????????????????????,????????????????,??,???????????????????,?????????????,??????????????

??:“??????????,???,????????????”

?????????????,???????????,???,?????????????????????“?????????????????”,?????,????????????,?,??????????,???,????,???????????

??,???????“1+3+N”??,??????????“N”??????????,??????????????,??????????????????“N”???,????????

??????????????????,????

???“?????”?????,??????????????????????????????????????,???????????????????

???????????,?,??????????,????????,????????

“?????????,?????????300??,???????????CAR-T???,CAR-T?????????????????????????,??,?,????‘?’????,?????????????,??????????,????????????????????????,???,??,???????????;?????????,???????????????????,????,???????‘????’?”????????????????

?“??”???????????,????????????,?????????????????

?????,???,???????????,???????,??????,????50???????,???,?????????,????????????????

??????????????????,??????,????????,??????????????????????????????????????,????

?????????????????????????,????,????????,??????“??????????”,?,????????????????????,?????????

????????,????????????????,??????,???????????

????????“??????”,?????,???????????????????????????

???????????????100?????????????????????CAR-T?????????????????????,?????????,???????,?????????????,???????????????CAR-T??26??,???????,?????4???????,??????

?????????“??????????????”,????????,??????????????,???

“???????????100??????,????CAR-T??,????????,????????????????????????????????????????????????,??????,???”?,?????,?????????;??????????;???????,??,???????

CAR-T????

?????????????????????CAR-T?????,?????:CAR-T?????????????????????????CAR-T???

?????CAR-T???,????????????????,??????????????????,???????CAR-T????????,???????????????????????,??????????????

???,?????????????????????“??????????????”??,??,?????????,???????“????????????????”??????????????,??????,????????????CAR-T???????????????,??????????,?????????????????

????,CAR-T???????,????????DRG/DIP?????,?“?????????????????????”?????????????????,?????????????“???????,??????,??”????

?????,“????????”???????????????,???????“??”????????????????????????????????,????????????????????CAR-T?????????????????????

“??CAR-T??????????50%~70%???”?????CAR-T???

??,???????????CAR-T???????,???????????????????????????,???,???????????CAR-T?????4.3??????????????????????????????,????CAR-T???????????????

??,??,CAR-T??????????????,????,?????????????????CAR-T???????????????????????????

????CAR-T???????????,????????????PD-1???????,CAR-T???,??,??????????,??,?????,???????????,??

??2024?????????????????3??????????????1???????CAR-T????????(???????)????,?? CAR-T??????????????11 ????????????????????,??????6???

????????“2025-2030????(CGT)???????????”???,??,????????CAR-T????????????????,2023???????????????????????????20%,????????184??,?168??????????????

???,????,??????CAR-T???????????????????????“?????????????????????”???

????????????????????,2032???????????CAR-T?????????????885.2???????????????????,?????“???????????????????????????,???????????”(??? ??????????????????????:??????) ???????????:??????????