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????????????????2025?????????2????21?????,?????????????????«??????»?“Base-modified nucleotides mediate immune signaling in bacteria(???????????)”?????(??)???????????????????????,??“??????”(Kongming),?“??????????????????”????,??????????????

??,???????,???????????“?????????????????”???1950?????(??????????????????cAMP?cGMP)?????????????????????,??????????????????????,????????????????,?????????????,????,??????????????????KomA(??????A)?KomB(???????B)?KomC(???C)?????,??????????(DNK)???????????“?”:KomA??????DNK????????????????????????????,?(dAMP)???????dITP???????????KomC????????????NAD⁺,????????????“?”?????????????????,??,????“??????”??????,???“??????”??????????,???????

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